Efeito da administração de ácido valpróico no comportamento de brincar na prole de ratos: um modelo animal para autismo

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dc.contributor.advisorMercadante, Marcos Tomanikpt_BR
dc.contributor.advisor-co1Bernardi, Maria Marthapt_BR
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/1013687028833943por
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/5141090677978994por
dc.contributor.authorCampos, Maria Lucila Ribeiropt_BR
dc.creator.Latteshttp://lattes.cnpq.br/2013924058437398por
dc.date.accessioned2016-03-15T19:40:23Z
dc.date.accessioned2020-03-19T15:20:09Z
dc.date.available2006-09-19pt_BR
dc.date.available2020-03-19T15:20:09Z
dc.date.issued2006-09-12pt_BR
dc.description.abstractAutism is a pervasive development disorder characterized by impairment in three areas: sociability, communication and repetitive behaviors, having a multicausal etiology, including genetic and environmental agents. In the late years, the seizures treatment with VPA during pregnancy has been related to higher occurrence of autism. In order to investigate the possible causes of autism, animal models had been used with expressive results. This study explores the impact in the sociability development in animals exposed to VPA during gestation. Pregnant rats were treated VPA in the 9th day of gestation and social behavior of the offspring were analyzed. The results showed a significant impairment in several forms of social behavior. Recent publications show abnormal serotonin neuron migration associated with VPA which might be underlying the mechanisms of these behaviors.eng
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dc.identifier.citationCAMPOS, Maria Lucila Ribeiro. Efeito da administração de ácido valpróico no comportamento de brincar na prole de ratos: um modelo animal para autismo. 2006. 56 f. Dissertação (Mestrado em Psicologia) - Universidade Presbiteriana Mackenzie, São Paulo, 2006.por
dc.identifier.urihttp://dspace.mackenzie.br/handle/10899/22577
dc.languageporpor
dc.publisherUniversidade Presbiteriana Mackenziepor
dc.rightsAcesso Abertopor
dc.subjectácido valpróicopor
dc.subjectautismopor
dc.subjectsociabilidadepor
dc.subjectautismeng
dc.subjectsociabilityeng
dc.subject.cnpqCNPQ::CIENCIAS BIOLOGICAS::ZOOLOGIA::COMPORTAMENTO ANIMALpor
dc.thumbnail.urlhttp://tede.mackenzie.br/jspui/retrieve/3936/MARIA%20LUCILA%20RIBEIRO%20CAMPOS%20-%20DD2006.pdf.jpg*
dc.titleEfeito da administração de ácido valpróico no comportamento de brincar na prole de ratos: um modelo animal para autismopor
dc.typeDissertaçãopor
local.contributor.board1Chiavegatto, Silvanapt_BR
local.contributor.board1Latteshttp://lattes.cnpq.br/4639530865431823por
local.publisher.countryBRpor
local.publisher.departmentPsicologiapor
local.publisher.initialsUPMpor
local.publisher.programDistúrbios do Desenvolvimentopor
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