Caldensinic acid, a prenylated benzoic acid from Piper caldense
Tipo
Artigo
Data de publicação
2009
Periódico
Phytochemistry Letters
Citações (Scopus)
11
Autores
Freitas G.C.
Kitamura R.O.S.
Lago J.H.G.
Young M.C.M.
Guimaraes E.F.
Kato M.J.
Kitamura R.O.S.
Lago J.H.G.
Young M.C.M.
Guimaraes E.F.
Kato M.J.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
The CH2Cl2 and MeOH extracts from leaves of Piper caldense were subjected to chromatographic separation procedures to afford the new prenylated benzoic acid, caldensinic acid (3-[(2′E,6′E,10′E)-11′-carboxy-3′,7′,15′-trimethylhexadeca-2′,6′,10′,14′-tetraenyl]-4,5-dihydroxybenzoic acid) whose structure was determined by spectral analysis, mainly NMR (1H, 13C, HSQC, HMBC) and ESI-MS. The natural compound and derivatives displayed antifungal activity against the phytopathogenic fungi Cladosporium cladosporioides and C. sphaerospermum by direct bioautography. © 2009 Phytochemical Society of Europe.