Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae)

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dc.contributor.authorGrecco S.S.
dc.contributor.authorReimao J.Q.
dc.contributor.authorTempone A.G.
dc.contributor.authorSartorelli P.
dc.contributor.authorRomoff P.
dc.contributor.authorFerreira M.J.P.
dc.contributor.authorFavero O.A.
dc.contributor.authorLago J.H.G.
dc.date.accessioned2024-03-13T01:31:52Z
dc.date.available2024-03-13T01:31:52Z
dc.date.issued2010
dc.description.abstractIn the course of selection of new bioactive compounds from Brazilian flora, the crude MeOH extract from the leaves of Baccharis retusa DC. (Asteraceae) showed potential against Leishmania sp. and Trypanosoma cruzi. Chromatographic fractionation of the dichloromethane phase from MeOH extract yielded great amounts of the bioactive derivative, which was characterized as 5,6,7-trihydroxy-4′-methoxyflavanone. The structure of this compound was established on the basis of spectroscopic data analysis, mainly nuclear magnetic resonance and mass spectrometry. © Springer-Verlag 2010.
dc.description.firstpage1245
dc.description.issuenumber5
dc.description.lastpage1248
dc.description.volume106
dc.identifier.doi10.1007/s00436-010-1771-8
dc.identifier.issn0932-0113
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37203
dc.relation.ispartofParasitology Research
dc.rightsAcesso Restrito
dc.titleIsolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae)
dc.typeArtigo
local.scopus.citations51
local.scopus.eid2-s2.0-77953286008
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77953286008&origin=inward
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