Therapeutic use of tetrodotoxin in animals Emprego terapêutico da tetrodotoxina em organismos animais

Página do item simplificado
dc.contributor.authorGomes A.P.
dc.contributor.authorDos Santos A.
dc.contributor.authorAmbrosio C.E.
dc.contributor.authorRibeiro M.O.
dc.date.accessioned2024-03-13T01:09:50Z
dc.date.available2024-03-13T01:09:50Z
dc.date.issued2011
dc.description.abstractThe Tetrodotoxin (TTX) is a powerful neurotoxin produced by bacteria and is found in a fish from Tetraodontidea family, which has been studied since 1884. This toxin has ability to block voltage-dependent sodium channels through guanidine group that binds to the outer opening of the channel. Thanks to this ability tetrodotoxin presents the possibility to be used as a new therapy in several areas. The studies showed that the pharmacological activity of TTX has been extensively studied and its use has been seen in therapy related to chronic pain and neuropathic, the reduction of metastasis in cancer, therapy related diseases in the muscular, skeletal, motor and nervous systems. This toxin has been showing as a promising tool to new treatments.
dc.description.firstpage343
dc.description.issuenumber4
dc.description.lastpage350
dc.description.volume5
dc.identifier.issn1981-5484
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36908
dc.relation.ispartofActa Veterinaria Brasilica
dc.rightsAcesso Restrito
dc.subject.otherlanguageBall fish
dc.subject.otherlanguageDuchenne muscular dystrophy
dc.subject.otherlanguageTetrodotoxin
dc.titleTherapeutic use of tetrodotoxin in animals Emprego terapêutico da tetrodotoxina em organismos animais
dc.typeArtigo de revisão
local.scopus.citations0
local.scopus.eid2-s2.0-84861077159
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861077159&origin=inward
Arquivos
Coleções
Artigos de periódico