Celiac disease screening in Brazilian patients with osteoporosis Pesquisa de doença celíaca em pacientes Brasileiros com osteoporose

dc.contributor.authorGusso L.
dc.contributor.authorSimoes M.C.
dc.contributor.authorSkare T.L.
dc.contributor.authorNisihara R.
dc.contributor.authorBurkiewicz C.C.
dc.contributor.authorUtiyama S.
dc.date.accessioned2024-03-13T01:02:33Z
dc.date.available2024-03-13T01:02:33Z
dc.date.issued2014
dc.description.abstractObjective: To analyze if it is worthwhile to screen Brazilian osteoporotic patients for celiac disease (CD). Subjects and methods: One hundred patients with osteoporosis and 97 controls were evaluated for IgA-EmA (IgA anti-endomysial antibodies) by indirect immunofluorescence method and IgG-anti-tTG (tissue transglutaminase) by ELISA assay. Positive patients were invited to have gastrointestinal endoscopy with jejunal biopsy. Results: Two patients had positive IgG-anti-tTG test and one of them also showed positive IgA-EmA. Only the latter had a positive duodenal biopsy for CD. None of the controls were positive for either auto-antibodies. Conclusion: We observed low prevalence of CD in osteoporotic Brazilian patients. This finding does not support routine screening for CD in patients with osteoporosis in our geographic region. © ABE&M todos os direitos reservados.
dc.description.firstpage270
dc.description.issuenumber3
dc.description.lastpage273
dc.description.volume58
dc.identifier.doi10.1590/0004-2730000002919
dc.identifier.issn1677-9487
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36497
dc.relation.ispartofArquivos Brasileiros de Endocrinologia e Metabologia
dc.rightsAcesso Aberto
dc.subject.otherlanguageAuto-antibodies
dc.subject.otherlanguageCeliac disease
dc.subject.otherlanguageGluten
dc.subject.otherlanguageOsteoporosis
dc.titleCeliac disease screening in Brazilian patients with osteoporosis Pesquisa de doença celíaca em pacientes Brasileiros com osteoporose
dc.typeArtigo
local.scopus.citations6
local.scopus.eid2-s2.0-84901496324
local.scopus.subjectAged
local.scopus.subjectAutoantibodies
local.scopus.subjectBrazil
local.scopus.subjectCase-Control Studies
local.scopus.subjectCeliac Disease
local.scopus.subjectComorbidity
local.scopus.subjectFemale
local.scopus.subjectFluorescent Antibody Technique, Indirect
local.scopus.subjectHumans
local.scopus.subjectImmunoglobulin A
local.scopus.subjectMale
local.scopus.subjectOsteoporosis
local.scopus.subjectPrevalence
local.scopus.subjectTransglutaminases
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84901496324&origin=inward
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