Celiac disease screening in Brazilian patients with osteoporosis Pesquisa de doença celíaca em pacientes Brasileiros com osteoporose
Tipo
Artigo
Data de publicação
2014
Periódico
Arquivos Brasileiros de Endocrinologia e Metabologia
Citações (Scopus)
6
Autores
Gusso L.
Simoes M.C.
Skare T.L.
Nisihara R.
Burkiewicz C.C.
Utiyama S.
Simoes M.C.
Skare T.L.
Nisihara R.
Burkiewicz C.C.
Utiyama S.
Orientador
Título da Revista
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Título de Volume
Membros da banca
Programa
Resumo
Objective: To analyze if it is worthwhile to screen Brazilian osteoporotic patients for celiac disease (CD). Subjects and methods: One hundred patients with osteoporosis and 97 controls were evaluated for IgA-EmA (IgA anti-endomysial antibodies) by indirect immunofluorescence method and IgG-anti-tTG (tissue transglutaminase) by ELISA assay. Positive patients were invited to have gastrointestinal endoscopy with jejunal biopsy. Results: Two patients had positive IgG-anti-tTG test and one of them also showed positive IgA-EmA. Only the latter had a positive duodenal biopsy for CD. None of the controls were positive for either auto-antibodies. Conclusion: We observed low prevalence of CD in osteoporotic Brazilian patients. This finding does not support routine screening for CD in patients with osteoporosis in our geographic region. © ABE&M todos os direitos reservados.
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Assuntos Scopus
Aged , Autoantibodies , Brazil , Case-Control Studies , Celiac Disease , Comorbidity , Female , Fluorescent Antibody Technique, Indirect , Humans , Immunoglobulin A , Male , Osteoporosis , Prevalence , Transglutaminases