A betabaculovirus-encoded gp64 homolog codes for a functional envelope fusion protein

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dc.contributor.authorArdisson-Araujo D.M.P.
dc.contributor.authorMelo F.L.
dc.contributor.authorClem R.J.
dc.contributor.authorWolff J.L.C.
dc.contributor.authorRibeiro B.M.
dc.date.accessioned2024-03-13T00:55:37Z
dc.date.available2024-03-13T00:55:37Z
dc.date.issued2016
dc.description.abstract© 2016, American Society for Microbiology.The GP64 envelope fusion protein is a hallmark of group I alphabaculoviruses. However, the Diatraea saccharalis granulovirus genome sequence revealed the first betabaculovirus species harboring a gp64 homolog (disa118). In this work, we have shown that this homolog encodes a functional envelope fusion protein and could enable the infection and fusogenic abilities of a gp64-null prototype baculovirus. Therefore, GP64 may complement or may be in the process of replacing F protein activity in this virus lineage.
dc.description.firstpage1668
dc.description.issuenumber3
dc.description.lastpage1672
dc.description.volume90
dc.identifier.doi10.1128/JVI.02491-15
dc.identifier.issn1098-5514
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36109
dc.relation.ispartofJournal of Virology
dc.rightsAcesso Aberto
dc.titleA betabaculovirus-encoded gp64 homolog codes for a functional envelope fusion protein
dc.typeArtigo
local.scopus.citations12
local.scopus.eid2-s2.0-84958078545
local.scopus.subjectAnimals
local.scopus.subjectGenetic Complementation Test
local.scopus.subjectGranulovirus
local.scopus.subjectLepidoptera
local.scopus.subjectViral Fusion Proteins
local.scopus.subjectVirus Internalization
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84958078545&origin=inward
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