Resistance exercise and testosterone treatment alters the proportion of numerical density of capillaries of the left ventricle of aging Wistar rats

Página do item simplificado
dc.contributor.authorGoncalves L.
dc.contributor.authorDe Souza R.R.
dc.contributor.authorMaifrino L.B.M.
dc.contributor.authorCaperuto E.C.
dc.contributor.authorCarbone P.O.
dc.contributor.authorRodrigues B.
dc.contributor.authorGama E.F.
dc.date.accessioned2024-03-13T00:59:48Z
dc.date.available2024-03-13T00:59:48Z
dc.date.issued2014
dc.description.abstract© 2014 Informa UK Ltd.Changes in the heart compartments that leads to pathological cardiac hypertrophy can be related to testosterone reduction in aging males since heart cells are susceptible to androgens. Resistance exercise delays the changes of aging.Aim: This study aimed to analyze alterations of the left ventricle of aged rats subjected to resistance exercise with administration of testosterone.Methods: Wistar rats were divided into five groups: C Group (control), S Group (sedentary), ST Group (sedentary treated with testosterone), T Group (trained) and TT Group (trained and treated with testosterone), strength training protocol and testosterone treatment were 16 weeks long. All groups were sacrificed at 16 months except for C group, sacrificed at 13 months.Results: There was no change in the weight of the heart or the left ventricle between the groups. ST group showed increase in Nv [cap] density of capillaries and collagen, with no differences in interstitial space. Both trained groups (T and TT) showed increase in the numerical density of capillaries (Nv [cap]) and in the interstitial space, with no changes in collagen.Conclusion: Resistance exercise combined with testosterone triggered a response of compensatory adjustment in the increase of Nv [cap], collagen and interstitial space, increasing perfusion and nutrition to the heart.
dc.description.firstpage243
dc.description.issuenumber4
dc.description.lastpage247
dc.description.volume17
dc.identifier.doi10.3109/13685538.2014.919252
dc.identifier.issn1473-0790
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36345
dc.relation.ispartofAging Male
dc.rightsAcesso Restrito
dc.subject.otherlanguageAging and exercise
dc.subject.otherlanguageHeart capillaries
dc.subject.otherlanguageTestosterone supplementation
dc.titleResistance exercise and testosterone treatment alters the proportion of numerical density of capillaries of the left ventricle of aging Wistar rats
dc.typeArtigo
local.scopus.citations13
local.scopus.eid2-s2.0-84911920948
local.scopus.subjectAnimals
local.scopus.subjectCapillaries
local.scopus.subjectHeart Ventricles
local.scopus.subjectMale
local.scopus.subjectPhysical Conditioning, Animal
local.scopus.subjectRats, Wistar
local.scopus.subjectResistance Training
local.scopus.subjectTestosterone
local.scopus.subjectVentricular Function, Left
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84911920948&origin=inward
Arquivos
Coleções
Artigos de periódico