Dry eye and sjögren's syndrome in rheumatoid arthritis Olho seco e Sjögren secundário na artrite reumatóide

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dc.contributor.authorGehlen M.L.
dc.contributor.authorSkare T.L.
dc.contributor.authorSilva M.B.
dc.contributor.authorAntero D.C.
dc.contributor.authorMiyazaki F.
dc.contributor.authorParra A.G.M.
dc.date.accessioned2024-03-13T01:07:35Z
dc.date.available2024-03-13T01:07:35Z
dc.date.issued2012
dc.description.abstractObjective: To examine the prevalence of keratoconjuntivitis sicca and secondary Sjögren syndrome (SS) in patients with RA from Southern Brazil and to analyze their relationship with RA duration, activity and patient's functional class. Patients with rheumatoid arthritis (RA) may have keratoconjuntivitis sicca that can be considered an extra articular manifestation of this disease. Methods: We studied 82 RA patients for sicca symptoms, Schirmer test, DAS-28 (RA activity index) and functional class. Results: There were eye sicca symptoms in 57.3%, positive Schirmer test in 41.2% and Secondary SS in 24.3%. The presence of a positive Schirmer test or the secondary SS had no relation with disease duration (p=0.65 and 0.80), RA activity (p=0,42 and 0,25) and neither with the patient's functional class (p= 0.84 and 0.79). Conclusion: There is a high prevalence of sicca syndrome in RA patients; one fourth of them have secondary SS. Secondary SS and sicca syndrome occurrence is independent of underlying RA activity, duration and cumulative damage.
dc.description.firstpage36
dc.description.issuenumber1
dc.description.lastpage39
dc.description.volume71
dc.identifier.doi10.1590/S0034-72802012000100007
dc.identifier.issn0034-7280
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36781
dc.relation.ispartofRevista Brasileira de Oftalmologia
dc.rightsAcesso Aberto
dc.subject.otherlanguageDry eye/etiology
dc.subject.otherlanguageRheumatoid arthritis/complications
dc.subject.otherlanguageSjogren's syndrome/etiology
dc.titleDry eye and sjögren's syndrome in rheumatoid arthritis Olho seco e Sjögren secundário na artrite reumatóide
dc.typeArtigo
local.scopus.citations3
local.scopus.eid2-s2.0-84864397050
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84864397050&origin=inward
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