Dry eye and sjögren's syndrome in rheumatoid arthritis Olho seco e Sjögren secundário na artrite reumatóide
Tipo
Artigo
Data de publicação
2012
Periódico
Revista Brasileira de Oftalmologia
Citações (Scopus)
3
Autores
Gehlen M.L.
Skare T.L.
Silva M.B.
Antero D.C.
Miyazaki F.
Parra A.G.M.
Skare T.L.
Silva M.B.
Antero D.C.
Miyazaki F.
Parra A.G.M.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
Objective: To examine the prevalence of keratoconjuntivitis sicca and secondary Sjögren syndrome (SS) in patients with RA from Southern Brazil and to analyze their relationship with RA duration, activity and patient's functional class. Patients with rheumatoid arthritis (RA) may have keratoconjuntivitis sicca that can be considered an extra articular manifestation of this disease. Methods: We studied 82 RA patients for sicca symptoms, Schirmer test, DAS-28 (RA activity index) and functional class. Results: There were eye sicca symptoms in 57.3%, positive Schirmer test in 41.2% and Secondary SS in 24.3%. The presence of a positive Schirmer test or the secondary SS had no relation with disease duration (p=0.65 and 0.80), RA activity (p=0,42 and 0,25) and neither with the patient's functional class (p= 0.84 and 0.79). Conclusion: There is a high prevalence of sicca syndrome in RA patients; one fourth of them have secondary SS. Secondary SS and sicca syndrome occurrence is independent of underlying RA activity, duration and cumulative damage.