Oncogenic osteomalacia: Localization of underlying peripheral tumor with 99mTc-sestamibi scintigraphy Osteomalácia oncogênica: Cintilografia com sestamibi- 99mTc na localização do tumor periférico

dc.contributor.authorBiagini G.L.K.
dc.contributor.authorCoutinho P.R.
dc.contributor.authorJonasson T.H.
dc.contributor.authorUeda C.E.
dc.contributor.authorGama R.R.
dc.date.accessioned2024-03-13T01:36:45Z
dc.date.available2024-03-13T01:36:45Z
dc.date.issued2008
dc.description.abstractOncogenic osteomalacia is a paraneoplastic syndrome usually induced by bone or soft tissue tumors. It is presented by the development of pain and fractures with hypophosphatemia, hyperphosphaturia, and inappropriate normal/low plasma 1,25(OH) 2D 3 concentration. After the removal of the tumor the complete resolution of all biochemical and clinical abnormalities is the main characteristic. A case of a 44-year-old female with difficulty in walking due to leg pain and generalized muscle weakness and hypophosphatemia, with relative hyperphosphaturia, is described. A whole-body 99mTc- sestamibi scintigraphy showed accumulation in the left thigh region, and a small tumor was detected by ultrasound examination. By removal of the tumor, a lipoma, the symptoms improved significantly after a month, with complete recovery by the fourth month. In this case, 99mTc-sestamibi scintigraphy was useful in identifying the location of the tumor, which caused oncogenic osteomalacia. Copyright© ABE&M.
dc.description.firstpage1505
dc.description.issuenumber9
dc.description.lastpage1509
dc.description.volume52
dc.identifier.doi10.1590/S0004-27302008000900016
dc.identifier.issn0004-2730
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37475
dc.relation.ispartofArquivos Brasileiros de Endocrinologia e Metabologia
dc.rightsAcesso Aberto
dc.subject.otherlanguage99mTc-sestamibi
dc.subject.otherlanguageHypophosphatemia
dc.subject.otherlanguageLipoma
dc.subject.otherlanguageMesenchymal tumor
dc.subject.otherlanguageNuclear medicine
dc.subject.otherlanguageOncogenic osteomalacia
dc.titleOncogenic osteomalacia: Localization of underlying peripheral tumor with 99mTc-sestamibi scintigraphy Osteomalácia oncogênica: Cintilografia com sestamibi- 99mTc na localização do tumor periférico
dc.typeArtigo
local.scopus.citations6
local.scopus.eid2-s2.0-60149086186
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=60149086186&origin=inward
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