The neurobiological bases of obsessive-compulsive disorder and Tourette syndrome As bases neurobiológicas do transtorno obsessivo-compulsivo e da síndrome de Tourette.
| dc.contributor.author | Mercadante M.T. | |
| dc.contributor.author | Rosario-Campos M.C. | |
| dc.contributor.author | Quarantini L.C. | |
| dc.contributor.author | Sato F.P. | |
| dc.date.accessioned | 2024-03-13T01:45:09Z | |
| dc.date.available | 2024-03-13T01:45:09Z | |
| dc.date.issued | 2004 | |
| dc.description.abstract | OBJECTIVE: To describe and discuss evidence-based articles on the neurobiology of obsessive-compulsive disorder and Tourette syndrome. SOURCES OF DATA: A review of the most relevant papers on the phenomenology, neuroanatomy, neuroimaging, genetic and immunological aspects of these two disorders was performed. SUMMARY OF THE FINDINGS: Ritualistic behaviors and repetitive thoughts have been extensively studied in the last years. The definitions of obsessive-compulsive disorder and Tourette syndrome emphasize the existence of a continuum of symptoms, with high prevalence in the general population. Neurobiological findings have implicated genetic and immunological factors in the etiology of these two disorders. CONCLUSIONS: Advances in neuroscience triggered genetic and immunological research studies, allowing new perspectives on the treatment of obsessive-compulsive disorder and Tourette syndrome patients. | |
| dc.description.issuenumber | 2 Suppl | |
| dc.description.volume | 80 | |
| dc.identifier.doi | 10.2223/jped.1167 | |
| dc.identifier.issn | 0021-7557 | |
| dc.identifier.uri | https://dspace.mackenzie.br/handle/10899/37937 | |
| dc.relation.ispartof | Jornal de pediatria | |
| dc.rights | Acesso Restrito | |
| dc.title | The neurobiological bases of obsessive-compulsive disorder and Tourette syndrome As bases neurobiológicas do transtorno obsessivo-compulsivo e da síndrome de Tourette. | |
| dc.type | Artigo de revisão | |
| local.scopus.citations | 12 | |
| local.scopus.eid | 2-s2.0-7444271405 | |
| local.scopus.updated | 2024-05-01 | |
| local.scopus.url | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=7444271405&origin=inward |