Efficacy of rTMS in decreasing postnatal depression symptoms: A systematic review

Página do item simplificado
dc.contributor.authorGanho-Avila A.
dc.contributor.authorPoleszczyk A.
dc.contributor.authorMohamed M.M.A.
dc.contributor.authorOsorio A.
dc.date.accessioned2024-03-12T23:52:12Z
dc.date.available2024-03-12T23:52:12Z
dc.date.issued2019
dc.description.abstract© 2019 Elsevier B.V.Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has been suggested as an alternative treatment to postnatal depression (PPD). Objectives: This systematic review aims to examine and summarise evidence on rTMS efficacy in treating depression during the postnatal period. Methods: We included randomized and non-randomized, single arm, and case report studies, with active rTMS and theta-burst stimulation, sham rTMS, pharmacotherapy or no treatment as comparators. Participants included women with PPD, who were administered rTMS after delivery and up to 12 months postpartum. The observed outcomes were response rate and acceptability. Results: rTMS shows promising results, with clinically significant decreases in Edinburgh Postnatal Depression Scale (EPDS) scores at week 4 and an overall low risk of dropout. Limitations: The reduced number of reports, the lack of complete datasets and the serious/high risk of bias of the studies warrant cautious interpretations. Conclusions and implications: Despite the promising results, existing evidence on rTMS efficacy is limited, and questions remain on what the most beneficial stimulation parameters should be. Future multicentre randomized clinical trials are needed to better ascertain the clinical efficacy of rTMS in the treatment of depression in the postpartum period.
dc.description.firstpage315
dc.description.lastpage322
dc.description.volume279
dc.identifier.doi10.1016/j.psychres.2019.05.042
dc.identifier.issn1872-7123
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35216
dc.relation.ispartofPsychiatry Research
dc.rightsAcesso Restrito
dc.titleEfficacy of rTMS in decreasing postnatal depression symptoms: A systematic review
dc.typeArtigo de revisão
local.scopus.citations16
local.scopus.eid2-s2.0-85066922517
local.scopus.subjectDepression, Postpartum
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectPregnancy
local.scopus.subjectPsychiatric Status Rating Scales
local.scopus.subjectRandomized Controlled Trials as Topic
local.scopus.subjectTranscranial Magnetic Stimulation
local.scopus.subjectTreatment Outcome
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066922517&origin=inward
Arquivos
Coleções
Artigos de periódico