Withanolides from Aureliana fasciculata var. fasciculata
| dc.contributor.author | Almeida-Lafeta R.C. | |
| dc.contributor.author | Ferreira M.J.P. | |
| dc.contributor.author | Emerenciano V.P. | |
| dc.contributor.author | Kaplan M.A.C. | |
| dc.date.accessioned | 2024-03-13T01:30:33Z | |
| dc.date.available | 2024-03-13T01:30:33Z | |
| dc.date.issued | 2010 | |
| dc.description.abstract | In the first phytochemical study of the Aureliana genus (Solanaceae), two new withanolides, 1 and 2, together with two known sterols, were isolated from the MeOH extract of the leaves of Aureliana fasciculata var. fasciculata. The structures were established as (4S,22R)-16α-acetoxy-5β,6β-epoxy- 4β,17α-dihydroxy-1-oxowitha-2,24-dienolide (aurelianolide A) and (4S,22R)-16α-acetoxy-4β,17α-dihydroxy-1-oxowitha-2,5, 24-trienolide (aurelianolide B). The new compounds possessed the unusual 16α,17α-dioxygenated group and were fully characterized by spectroscopic techniques, including 1H- and 13C-NMR (DEPT), as well as 2D-NMR (HMBC, HMQC, 1H,1H-COSY, NOESY) experiments, and HR-MS. © 2010 Verlag Helvetica Chimica Acta AG, Zürich. | |
| dc.description.firstpage | 2478 | |
| dc.description.issuenumber | 12 | |
| dc.description.lastpage | 2487 | |
| dc.description.volume | 93 | |
| dc.identifier.doi | 10.1002/hlca.201000126 | |
| dc.identifier.issn | 1522-2675 | |
| dc.identifier.uri | https://dspace.mackenzie.br/handle/10899/37130 | |
| dc.relation.ispartof | Helvetica Chimica Acta | |
| dc.rights | Acesso Restrito | |
| dc.subject.otherlanguage | Aureliana fasciculata var. fasciculata | |
| dc.subject.otherlanguage | Aurelianolides A and B | |
| dc.subject.otherlanguage | Withanolides | |
| dc.title | Withanolides from Aureliana fasciculata var. fasciculata | |
| dc.type | Artigo | |
| local.scopus.citations | 16 | |
| local.scopus.eid | 2-s2.0-78650338695 | |
| local.scopus.subject | Aureliana fasciculata var. fasciculata | |
| local.scopus.subject | Aurelianolides A and B | |
| local.scopus.subject | Solanaceae | |
| local.scopus.subject | Spectroscopic technique | |
| local.scopus.subject | Withanolides | |
| local.scopus.updated | 2024-05-01 | |
| local.scopus.url | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78650338695&origin=inward |