3-Ishwarone and 3-ishwarol, rare sesquiterpenes in essential oil from leaves of Peperomia oreophila Hensch.
Tipo
Artigo
Data de publicação
2007
Periódico
Journal of the Brazilian Chemical Society
Citações (Scopus)
18
Autores
Lago J.H.G.
De Oliveira A.
Guimaraes E.F.
Kato M.J.
De Oliveira A.
Guimaraes E.F.
Kato M.J.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
The essential oil from Peperomia oreophila leaves (Piperaceae) was submitted to fractionation in silica gel column. This separation procedure yielded a fraction composed of a hydrocarbon sesquiterpene mixture which was identified as β-elemene, α-ylangene, α-guaiene and β-selinene. Besides, spathulenol and two sesquiterpenes with the rare ishwarane skeleton: 3-ishwarol and 3-ishwarone were also identified. 3-ishwarone was the major component of the crude oil (78% weight). Since the alcohol obtained was not sufficient to allow a complete structural determination, the original ketone was reduced to 3-ishwarol in order to give additional quantities. After the two sesquiterpenes purification, they were characterized by spectrometric techniques (1H-1H COSY, HMQC, HMBC and NOESY). ©2007 Sociedade Brasileira de Química.