Prevalence of cutaneous findings in systemic sclerosis patients - Experience of a teaching hospital Prevalência de achados cutâneos em portadores de esclerose sistêmica - Experiência de um hospital universitário

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dc.contributor.authorGuidolin F.
dc.contributor.authorEsmanhotto L.
dc.contributor.authorMagro C.E.
dc.contributor.authorBarreto Silva M.
dc.contributor.authorSkare T.L.
dc.date.accessioned2024-03-13T01:44:14Z
dc.date.available2024-03-13T01:44:14Z
dc.date.issued2005
dc.description.abstractBACKGROUND - Systemic sclerosis or scleroderma is a rare collagen disease presenting several cutaneous manifestations. OBJECTIVE - To study the prevalence of cutaneous manifestations in systemic sclerosis and its subtypes (limited form, diffuse form and overlap syndrome). METHODS - We studied 32 patients with scleroderma (20 with the limited form; 8 with the diffuse form and 4 with overlap syndrome) considering skin sclerosis, Raynaud's phenomenon, digital scars, telangiectasia, leucomelanoderma (pigmentary changes), microstomy, calcinosis and pruritus. RESULTS - We found skin sclerosis and Raynaud's phenomenon in 100% of patients, digital scars in 65.6%, telangiectasia in 43.7% pigmentary changes in 43.7% microstomy in 31.25% pruritus in 28.1% and calcinosis in 12.5%. No statistically significant differences were observed in the limited and diffuse forms of scleroderma (p = 1.0 for digital scars; p = 0.69 for teleangiectasis; p = 0.22 for microstomy; p = 1.0 for calcinosis and pruritus). The overlap syndrome was not different from the isolated forms (limited and diffuse) of systemic sclerosis. CONCLUSION - The most common skin manifestations in scleroderma are skin sclerosis and Raynaud's phenomenon and calcinosis is the rarest. The other cutaneous manifestations presented similar frequency in all subtypes of scleroderma. ©2005 by Anais Brasileiros de Dermatologia.
dc.description.firstpage481
dc.description.issuenumber5
dc.description.lastpage486
dc.description.volume80
dc.identifier.doi10.1590/s0365-05962005000600005
dc.identifier.issn1806-4841
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37886
dc.relation.ispartofAnais Brasileiros de Dermatologia
dc.rightsAcesso Aberto
dc.subject.otherlanguageMixed connective tissue disease
dc.subject.otherlanguageScleroderma, diffuse
dc.subject.otherlanguageScleroderma, limited
dc.subject.otherlanguageScleroderma, systemic
dc.titlePrevalence of cutaneous findings in systemic sclerosis patients - Experience of a teaching hospital Prevalência de achados cutâneos em portadores de esclerose sistêmica - Experiência de um hospital universitário
dc.typeArtigo
local.scopus.citations7
local.scopus.eid2-s2.0-33846674220
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846674220&origin=inward
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