Skull base chordomas: Surgical management, results, and complications in 31 patients Cordomas de la base del cráneo: Manejo quirúrgico, resultados y complicaciones en 31 pacientes
Tipo
Artigo
Data de publicação
2013
Periódico
Revista Mexicana de Neurociencia
Citações (Scopus)
0
Autores
Ali D.-C.
Cassio Z.-G.
Roberta R.
Borba Luis A.B.
Cassio Z.-G.
Roberta R.
Borba Luis A.B.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
INTRODUCTION: Chordoma is an uncommon, slow-growing tumor, locally invasive and destructive, arising from notochordal remnants. It originates from skull base central portion, demonstrating different patterns of invasiveness, including duramater penetration and its spread through vascular structures, compromising its completely resection. OBJECTIVE: To analyze the different options of treatment, results, and complications. METHODS: Between 2002 and 2012, 31 patients presenting skull base chordomas were treated surgically at the Evangelico University Hospital of Curitiba, Curitiba-Brazil. The follow-up period was 1-72 months. All patients were evaluated by means of head CT and MRI. Surgical approaches were chosen for each specific case, aiming to obtain a tumor radical resection. Some patients were submitted to radiotherapy after surgical resection. RESULTS: Radical resection was performed in 81% of the patients. A five-year survival rate was 75%. Radical resection had a positive impact on the survival rate. The possibility to perform a radical resection depended on the tumor volume pre-operation and number of anatomic regions invaded. The sixth cranial nerve palsy and CSF fistula were the most common surgical complications. CONCLUSION: The purpose of the surgical management treating skull base chordomas consists in performing radical resection using different types of surgical approaches, which implies an acceptable risk.