Non-enzymatic biosensor based on F,S-doped carbon dots/copper nanoarchitecture applied in the simultaneous electrochemical determination of NADH, dopamine, and uric acid in plasma

Tipo
Artigo
Data de publicação
2024
Periódico
Analyst
Citações (Scopus)
5
Autores
de Souza O.P.L.
Tiba D.Y.
Ferreira J.H.A.
Lieb L.C.
Canevari T.C.
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Resumo
© 2024 The Royal Society of ChemistryThis work presents the synthesis and characterization of an innovative F,S-doped carbon dots/CuONPs hybrid nanostructure obtained by a direct mixture between F,S-doped carbon dots obtained electrochemically and copper nitrate alcoholic solution. The hybrid nanostructures synthesized were characterized by absorption spectroscopy in the Ultraviolet region (UV-vis), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), and different electrochemical techniques. The fluoride and sulfur-doped carbon dots/CuONPs nanostructures were used to prepare a non-enzymatic biosensor on a printed carbon electrode, exhibiting excellent electrocatalytic activity for the simultaneous determination of NADH, dopamine, and uric acid in the presence of ascorbic acid with a detection limit of 20, 80, and 400 nmol L−1, respectively. The non-enzymatic biosensors were also used to determine NADH, dopamine, and uric acid in plasma, and they did not suffer significant interference from each other.
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Carbon dots , Dopamine , Doped carbons , Electrochemical determination , Hybrid nanostructures , Nano-architecture , Non-enzymatic biosensors , S-doped , Synthesis and characterizations , Uric acids , Biosensing Techniques , Carbon , Copper , Dopamine , Electrochemical Techniques , Electrodes , Fluorides , Humans , Limit of Detection , NAD , Nanostructures , Quantum Dots , Sulfur , Uric Acid
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