Assessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder

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dc.contributor.authorSchuch J.B.
dc.contributor.authorBecker N.
dc.contributor.authorRabelo-Da-ponte F.D.
dc.contributor.authorOrnell F.
dc.contributor.authorFreitas H.J.M.
dc.contributor.authorRebelatto F.P.
dc.contributor.authorSordi A.O.
dc.contributor.authorPechansky F.
dc.contributor.authorvon Diemen L.
dc.contributor.authorKessler F.H.P.
dc.date.accessioned2024-03-12T19:11:18Z
dc.date.available2024-03-12T19:11:18Z
dc.date.issued2023
dc.description.abstract© 2023, Sociedade de Psiquiatria do Rio Grande do Sul. All rights reserved.Introduction: Consumption of substances has been associated with cognitive impairment. The Mini Mental State Examination (MMSE) is an easy-to-apply screening tool used to assess cognitive functions. Objectives: To evaluate the cognitive performance of individuals with alcohol (AUD) and/or crack cocaine use disorder (CUD) and polysubstance use using the MMSE and to investigate the impact of substance use profile and the moderation effect of educational level on MMSE performance. Methods: Cross-sectional study with 508 adult male inpatients diagnosed with substance use disorders (245 with AUD, 85 with CUD, and 178 with polysubstance use). Cognitive performance was assessed using the MMSE scale (total and composite scores). Results: Individuals with AUD had worse total MMSE scores and scored worse for all three MMSE components compared to individuals with polysubstance use (p < 0.001, oral/written language comprehension, p < 0.001, attention/memory, and p = 0.007, motor functions). MMSE scores were positively correlated with educational level (p < 0.017), but were not associated with age, recent drug use, or years of drug use. Educational level moderated the impact of substance use on MMSE performance, especially total score and composite language comprehension score. Individuals with a low educational level (≤ 8 years) had worse performance than those with a high educational level (≥ 9 years), mainly in individuals with AUD (p < 0.001). Discussion: Individuals with a low educational level and alcohol use are more prone to present cognitive impairment than crack cocaine users, especially involving language aspects. Better-preserved cognitive function could impact treatment adherence and might guide the decision of therapeutic strategies.
dc.description.volume45
dc.identifier.doi10.47626/2237-6089-2022-0567
dc.identifier.issn2237-6089
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/34167
dc.relation.ispartofTrends in Psychiatry and Psychotherapy
dc.rightsAcesso Aberto
dc.subject.otherlanguagealcohol-related disorders
dc.subject.otherlanguagecocaine
dc.subject.otherlanguagecocaine smoking
dc.subject.otherlanguagelanguage comprehension
dc.subject.otherlanguageSubstance-related disorders
dc.titleAssessment of cognitive functioning using the Mini Mental State Examination in men with alcohol and crack cocaine use disorder
dc.typeArtigo
local.scopus.citations2
local.scopus.eid2-s2.0-85172284759
local.scopus.subjectAdult
local.scopus.subjectCognition
local.scopus.subjectCrack Cocaine
local.scopus.subjectCross-Sectional Studies
local.scopus.subjectEthanol
local.scopus.subjectHumans
local.scopus.subjectMale
local.scopus.subjectMental Status and Dementia Tests
local.scopus.subjectSubstance-Related Disorders
local.scopus.updated2024-12-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85172284759&origin=inward
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