Metabolic syndrome and psoriasis: A study in 97 patients

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dc.contributor.authorFerdinando L.B.
dc.contributor.authorFukumoto P.K.
dc.contributor.authorSanches S.
dc.contributor.authorFabricio L.H.Z.
dc.contributor.authorSkare T.L.
dc.date.accessioned2024-03-12T23:58:06Z
dc.date.available2024-03-12T23:58:06Z
dc.date.issued2018
dc.description.abstract© 2018 Associacao Medica Brasileira. All rights reserved.BACKGROUND: Psoriasis is associated with higher prevalence of metabolic syndrome (MS). The prevalence of MS varies according to the studied population as it suffers influence of genetics, aging, sedentary behaviour and diet. OBJECTIVE: To study the prevalence of MS in local psoriasis patients and the influence of psoriasis variables on its appearance. METHODS: A group of 97 psoriasis patients were studied for MS and compared with 97 controls. Psoriasis type, nail involvement, psoriasis extension measured by PASI (Psoriasis Area and Severity Index) were obtained through physical examination and history of previous myocardial infarction, angina and stroke were obtained through chart review. RESULTS: Comparison of MS prevalence in psoriasis patients (49.4%) with controls (35.0%) showed difference with p=0.04; OR=1.8 (95%CI=1.02-3.23). Patients with psoriasis had higher body mass index (p=0.02), higher systolic blood pressure (p=0.007), lower HDL cholesterol (p=0.01), higher glucose (p=0.04), higher waist circumference (p=0.003) and more angina pectoris (p=0.03;OR=2.5; 95% CI=1.04-6.15) than controls. When psoriasis sample with and without MS were compared, those with MS were older (p=0.0004), had disease onset at older age (p=0.02), more tobacco exposure (p=0.02), and a tendency to have less scalp involvement (p=0.06) in univariate analysis. Logistic regression showed that only age and scalp involvement were independently associated with MS in the psoriasis sample. CONCLUSION: In our psoriasis sample, MS prevalence is high and the items that deserve more attention are central obesity, low HDL, hypertension and smoking habits. In the psoriasis group, MS was associated independently with older age and less scalp involvement.
dc.description.firstpage368
dc.description.issuenumber4
dc.description.lastpage373
dc.description.volume64
dc.identifier.doi10.1590/1806-9282.64.04.368
dc.identifier.issn0104-4230
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35543
dc.relation.ispartofRevista da Associacao Medica Brasileira
dc.rightsAcesso Aberto
dc.subject.otherlanguageMetabolic diseases
dc.subject.otherlanguageMetabolic syndrome X
dc.subject.otherlanguagePsoriasis
dc.titleMetabolic syndrome and psoriasis: A study in 97 patients
dc.typeArtigo
local.scopus.citations20
local.scopus.eid2-s2.0-85052993464
local.scopus.subjectAdult
local.scopus.subjectAge Factors
local.scopus.subjectAged
local.scopus.subjectAged, 80 and over
local.scopus.subjectBlood Glucose
local.scopus.subjectBlood Pressure
local.scopus.subjectBrazil
local.scopus.subjectCase-Control Studies
local.scopus.subjectCholesterol, HDL
local.scopus.subjectCross-Sectional Studies
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectLogistic Models
local.scopus.subjectMale
local.scopus.subjectMetabolic Syndrome
local.scopus.subjectMiddle Aged
local.scopus.subjectObesity, Abdominal
local.scopus.subjectPrevalence
local.scopus.subjectPsoriasis
local.scopus.subjectSeverity of Illness Index
local.scopus.subjectStatistics, Nonparametric
local.scopus.subjectTriglycerides
local.scopus.subjectWaist Circumference
local.scopus.subjectYoung Adult
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85052993464&origin=inward
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