Omega-3 consumption and sudden cardiac death in schizophrenia

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dc.contributor.authorScorza F.A.
dc.contributor.authorCysneiros R.M.
dc.contributor.authorTerra V.C.
dc.contributor.authorScorza C.A.
dc.contributor.authorCavalheiro E.A.
dc.contributor.authorRibeiro M.O.
dc.contributor.authorGattaz W.F.
dc.date.accessioned2024-03-13T01:34:13Z
dc.date.available2024-03-13T01:34:13Z
dc.date.issued2009
dc.description.abstractPeople with schizophrenia show a two- to three-fold increased risk to die prematurely. Mortality is accounted for by a combination of factors (patients' life style, suicide, premature cardiovascular disease, metabolic syndromes and, not so often mentioned, sudden death). The cause of sudden death in schizophrenia is unknown, but cardiac arrhythmia plays a potential role. Patients with schizophrenia are at high risk for cardiovascular disease, and some antipsychotics may be associated with cardiovascular adverse events (e.g., electrocardiograph QT interval prolongation), suggesting that this could lead to sudden cardiac death. Animal and clinical studies have shown that omega-3 fatty acids could be useful in the prevention and treatment of schizophrenia. As omega-3 fatty acids have been considered a cardioprotector agent, reducing cardiac arrhythmias and hence sudden cardiac deaths and given their relative safety and general health benefits, our update article summarizes the knowledge by the possible positive effects of omega-3 supplementation and fish consumption against sudden cardiac death in patients with schizophrenia. However, fish species should be selected with caution due to contamination with toxic methylmercury. © 2009 Elsevier Ltd. All rights reserved.
dc.description.firstpage241
dc.description.issuenumber4
dc.description.lastpage245
dc.description.volume81
dc.identifier.doi10.1016/j.plefa.2009.06.008
dc.identifier.issn0952-3278
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37334
dc.relation.ispartofProstaglandins Leukotrienes and Essential Fatty Acids
dc.rightsAcesso Restrito
dc.subject.otherlanguageFish.
dc.subject.otherlanguageHeart
dc.subject.otherlanguageOmega-3
dc.subject.otherlanguageSchizophrenia
dc.subject.otherlanguageSudden cardiac death
dc.titleOmega-3 consumption and sudden cardiac death in schizophrenia
dc.typeArtigo
local.scopus.citations25
local.scopus.eid2-s2.0-70349632228
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70349632228&origin=inward
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