Chemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects

dc.contributor.authorRetamozo M.H.
dc.contributor.authorSilva C.C.
dc.contributor.authorTamayose C.I.
dc.contributor.authorCarvalho J.C.S.
dc.contributor.authorRomoff P.
dc.contributor.authorFavero O.A.
dc.contributor.authorFerreira M.J.P.
dc.date.accessioned2024-03-12T19:10:04Z
dc.date.available2024-03-12T19:10:04Z
dc.date.issued2023
dc.description.abstract© 2023 by the authors.Baccharis is one of the largest genera of Asteraceae and its species are used in folk medicine for several medicinal purposes due to the presence of bioactive compounds. We investigated the phytochemical composition of polar extracts of B. sphenophylla. Using chromatographic procedures, diterpenoids (ent-kaurenoic acid), flavonoids (hispidulin, eupafolin, isoquercitrin, quercitrin, biorobin, rutin, and vicenin-2), caffeic acid, and chlorogenic acid derivatives (5-O-caffeoylquinic acid and its methyl ester, 3,4-di-O-caffeoylquinic acid, 4,5-di-O-caffeoylquinic acid, and 3,5-di-O-caffeoylquinic acid and its methyl ester) were isolated from polar fractions and are described. The extract, polar fractions, and fifteen isolated compounds were evaluated in relation to radical scavenging activity using two assays. Chlorogenic acid derivatives and flavonols exhibited higher antioxidant effects, confirming that B. sphenophylla is an important source of phenolic compounds with antiradical properties.
dc.description.issuenumber6
dc.description.volume12
dc.identifier.doi10.3390/plants12061262
dc.identifier.issn2223-7747
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/34101
dc.relation.ispartofPlants
dc.rightsAcesso Aberto
dc.subject.otherlanguageantiradical activity
dc.subject.otherlanguageBaccharis sphenophylla
dc.subject.otherlanguagechlorogenic acid derivatives
dc.subject.otherlanguageCompositae
dc.subject.otherlanguageflavonoids
dc.titleChemical Constituents from Leaves of Baccharis sphenophylla (Asteraceae) and Their Antioxidant Effects
dc.typeArtigo
local.scopus.citations7
local.scopus.eid2-s2.0-85151437930
local.scopus.updated2025-04-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85151437930&origin=inward
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