Secondary metabolites isolated from Piper chimonantifolium and their antifungal activity
Tipo
Artigo
Data de publicação
2012
Periódico
Natural Product Research
Citações (Scopus)
11
Autores
Lago J.H.G.
Ito A.T.
Fernandes C.M.
Young M.C.M.
Kato M.J.
Ito A.T.
Fernandes C.M.
Young M.C.M.
Kato M.J.
Orientador
Título da Revista
ISSN da Revista
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Resumo
In this study, the CH2Cl2 extract from leaves of Piper chimonantifolium was subjected to several chromatographic separation procedures to afford one chromene (gaudichaudianic acid) as a major compound as well as two flavonoids (dihydrooroxylin and pinocembrin) and three steroids (sitosterol, sitosteryl palmitate and stigmasterol). The structures of all determined compounds were characterised by spectrometric analysis, mainly mass spectrometry and NMR, as well as their optical properties. This article describes the first phytochemical study of the leaves of P. chimonantifolium and an evaluation of the antifungal activity of its major compounds. © 2011 Taylor & Francis.