Transcranial direct-current stimulation induced in stroke patients with aphasia: A prospective experimental cohort study Estimulação transcraniana por corrente contínua para afasia após acidente vascular cerebral: Estudo de coorte único experimental prospectivo

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dc.contributor.authorSantos M.D.
dc.contributor.authorGagliardi R.J.
dc.contributor.authorMac-Kay A.P.M.G.
dc.contributor.authorBoggio P.S.
dc.contributor.authorLianza R.
dc.contributor.authorFregni F.
dc.date.accessioned2024-03-13T01:02:59Z
dc.date.available2024-03-13T01:02:59Z
dc.date.issued2013
dc.description.abstractContext and Objective: Previous animal and human studies have shown that transcranial direct current stimulation can induce significant and lasting neuroplasticity and may improve language recovery in patients with aphasia. The objective of the study was to describe a cohort of patients with aphasia after stroke who were treated with transcranial direct current stimulation. Design and Setting: Prospective cohort study developed in a public university hospital. Methods: Nineteen patients with chronic aphasia received 10 transcranial direct current stimulation sessions lasting 20 minutes each on consecutive days, using a current of 2 mA. The anode was positioned over the supraorbital area and the cathode over the contralateral motor cortex. The following variables were analyzed before and after the 10 neuromodulation sessions: oral language comprehension, copying, dictation, reading, writing, naming and verbal fluency. Results: There were no adverse effects in the study. We found statistically significant differences from before to after stimulation in relation to simple sentence comprehension (P = 0.034), naming (P = 0.041) and verbal fluency for names of animals (P = 0.038). Improved scores for performing these three tasks were seen after stimulation. Conclusions: We observed that excitability of the primary motor cortex through transcranial direct current stimulation was associated with effects on different aspects of language. This can contribute towards future testing in randomized controlled trials.
dc.description.firstpage422
dc.description.issuenumber6
dc.description.lastpage426
dc.description.volume131
dc.identifier.doi10.1590/1516-3180.2013.1316595
dc.identifier.issn1516-3180
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36521
dc.relation.ispartofSao Paulo Medical Journal
dc.rightsAcesso Aberto
dc.subject.otherlanguageAphasia
dc.subject.otherlanguageElectric stimulation
dc.subject.otherlanguageLanguage disorders
dc.subject.otherlanguageSpeech disorders
dc.subject.otherlanguageStroke
dc.titleTranscranial direct-current stimulation induced in stroke patients with aphasia: A prospective experimental cohort study Estimulação transcraniana por corrente contínua para afasia após acidente vascular cerebral: Estudo de coorte único experimental prospectivo
dc.typeArtigo
local.scopus.citations18
local.scopus.eid2-s2.0-84890824692
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84890824692&origin=inward
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