Short report: Can we use a lower dose of liposomal amphotericin B for the treatment of mucosal American leishmaniasis?
Tipo
Artigo
Data de publicação
2011
Periódico
American Journal of Tropical Medicine and Hygiene
Citações (Scopus)
29
Autores
Amato V.S.
Tuon F.F.
Camargo R.A.
Souza R.M.
Santos C.R.
Nicodemo A.C.
Tuon F.F.
Camargo R.A.
Souza R.M.
Santos C.R.
Nicodemo A.C.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
Liposomal amphotericin B has been used as an alternative treatment of mucosal leishmaniasis, but the optimal dose is not established. We retrospectively reviewed the clinical outcome of eight patients with mucosal leishmaniasis treated with liposomal amphotericin B. The mean total dose was 35 mg/kg (range 24-50 mg/kg), which resulted in the healing of all the lesions in all patients and no recurrences were observed during the follow-up period (mean 25 months; range 7-40 months). Copyright © 2011 by The American Society of Tropical Medicine and Hygiene.