Hemispheric asymmetries in subcortical visual and auditory relay structures in congenital deafness

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dc.contributor.authorAmaral L.
dc.contributor.authorGanho-Avila A.
dc.contributor.authorOsorio A.
dc.contributor.authorSoares M.J.
dc.contributor.authorHe D.
dc.contributor.authorChen Q.
dc.contributor.authorMahon B.Z.
dc.contributor.authorGoncalves O.F.
dc.contributor.authorSampaio A.
dc.contributor.authorFang F.
dc.contributor.authorBi Y.
dc.contributor.authorAlmeida J.
dc.date.accessioned2024-03-13T00:52:27Z
dc.date.available2024-03-13T00:52:27Z
dc.date.issued2016
dc.description.abstract© 2016 Federation of European Neuroscience Societies and John Wiley & Sons LtdNeuroplasticity – the capacity of the brain to change as a response to internal and external pressures – has been studied from a number of different perspectives. Perhaps one of the most powerful models is the study of populations that have been congenitally deprived of a sense. It has been shown that the right Auditory Cortex (AC) of congenitally deaf humans is neuroplastically modified in order to represent visual properties of a stimulus. One unresolved question is how this visual information is routed to the AC of congenitally deaf individuals. Here, we performed volumetric analysis of subcortical auditory and visual brains regions – namely the thalamus (along with three thalamic nuclei: the pulvinar, the lateral geniculate nucleus and the medial geniculate nucleus), and the inferior and superior colliculi – in deaf and hearing participants in order to identify which structures may be responsible for relaying visual information toward the altered AC. Because there is a hemispheric asymmetry in the neuroplastic changes observed in the AC of the congenitally deaf, we reasoned that subcortical structures that also showed a similar asymmetry in their total volume could have been enlisted in the effort of relaying visual information to the neuroplastically altered right AC. We show that for deaf, but not for hearing individuals, the right thalamus, right lateral geniculate nucleus and right inferior colliculus are larger than their left counterparts. These results suggest that these subcortical structures may be responsible for rerouting visual information to the AC in congenital deafness.
dc.description.firstpage2334
dc.description.issuenumber6
dc.description.lastpage2339
dc.description.volume44
dc.identifier.doi10.1111/ejn.13340
dc.identifier.issn1460-9568
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35930
dc.relation.ispartofEuropean Journal of Neuroscience
dc.rightsAcesso Restrito
dc.subject.otherlanguageauditory cortex
dc.subject.otherlanguageneuroimaging
dc.subject.otherlanguageneuronal plasticity
dc.subject.otherlanguageocular vision
dc.subject.otherlanguagethalamus
dc.titleHemispheric asymmetries in subcortical visual and auditory relay structures in congenital deafness
dc.typeArtigo
local.scopus.citations12
local.scopus.eid2-s2.0-84987811127
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84987811127&origin=inward
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