Activation and involvement of the lateral-posterior nucleus of the thalamus after a single generalized tonic-clonic seizure

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dc.contributor.authorSonoda E.Y.D.F.
dc.contributor.authorCysneiros R.M.
dc.contributor.authorArida R.M.
dc.contributor.authorCavalheiro E.A.
dc.contributor.authorScorza F.A.
dc.date.accessioned2024-03-13T01:04:26Z
dc.date.available2024-03-13T01:04:26Z
dc.date.issued2013
dc.description.abstractThe lateral-posterior thalamic nuclei (LP) have been shown to play an important role in controlling epileptic activity. In addition, thalamic atrophy and neuronal loss have been observed in epilepsy. The objective of this study was to investigate whether lateral-posterior neuronal activation may be observed shortly after a single generalized seizure in rats submitted to the pilocarpine model of epilepsy. The results showed an increased lateral-posterior activation as soon as the seizure occurred, suggesting that neuronal loss in the thalamus is not only the consequence of chronic epilepsy. © 2013 Elsevier Inc.
dc.description.firstpage104
dc.description.issuenumber1
dc.description.lastpage107
dc.description.volume28
dc.identifier.doi10.1016/j.yebeh.2013.03.025
dc.identifier.issn1525-5050
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36603
dc.relation.ispartofEpilepsy and Behavior
dc.rightsAcesso Aberto
dc.subject.otherlanguageCell excitability
dc.subject.otherlanguageNeuronal activation
dc.subject.otherlanguageNeuronal loss
dc.subject.otherlanguagePilocarpine
dc.subject.otherlanguageSUDEP
dc.titleActivation and involvement of the lateral-posterior nucleus of the thalamus after a single generalized tonic-clonic seizure
dc.typeArtigo
local.scopus.citations3
local.scopus.eid2-s2.0-84878212975
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84878212975&origin=inward
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