Transcranial direct current stimulation of the unaffected hemisphere in stroke patients
Tipo
Artigo
Data de publicação
2005
Periódico
NeuroReport
Citações (Scopus)
526
Autores
Fregni F.
Boggio P.S.
Mansur C.G.
Wagner T.
Ferreira M.J.L.
Lima M.C.
Rigonatti S.P.
Marcolin M.A.
Freedman S.D.
Nitsche M.A.
Pascual-Leone A.
Boggio P.S.
Mansur C.G.
Wagner T.
Ferreira M.J.L.
Lima M.C.
Rigonatti S.P.
Marcolin M.A.
Freedman S.D.
Nitsche M.A.
Pascual-Leone A.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
Recovery of function after a stroke is determined by a balance of activity in the neural network involving both the affected and the unaffected brain hemispheres. Increased activity in the affected hemisphere can promote recovery, while excessive activity in the unaffected hemisphere may represent a maladaptive strategy. We therefore investigated whether reduction of the excitability in the unaffected hemisphere by cathodal transcranial direct current stimulation could result in motor performance improvement in stroke patients. We compared these results with excitability-enhancing a nodal transcranial direct current stimulation of the affected hemisphere and sham transcranial direct current stimulation. Both cathodal stimulation of the unaffected hemisphere and anodal stimulation of the affected hemisphere (but not sham transcranial direct current stimulation) improved motor performance significantly. These results suggest that the appropriate modulation of bihemispheric brain structures can promote motor function recovery. © 2005 Lippincott Williams & Wilkins.