Shape memory thermoplastic polyurethane/polycaprolactone blend and composite with hydroxyapatite for biomedical application

Pinto L.A.; Backes E.H.; Harb S.V.; Pinto G.M.; da Cunha D.A.L.V.; Andrade R.J.E.; Fechine G.J.M.; Selistre-de-Araujo H.S.; Costa L.C.; Pessan L.A.

Shape memory thermoplastic polyurethane/polycaprolactone blend and composite with hydroxyapatite for biomedical application

Tipo

Artigo

Data de publicação

2024

Periódico

Journal of Materials Research

Citações (Scopus)

13

Autores

Pinto L.A.
Backes E.H.
Harb S.V.
Pinto G.M.
da Cunha D.A.L.V.
Andrade R.J.E.
Fechine G.J.M.
Selistre-de-Araujo H.S.
Costa L.C.
Pessan L.A.

Resumo

© 2023, The Author(s).Depending on its composition, thermoplastic polyurethane (TPU)/polycaprolactone (PCL) blend may present interesting properties for biomedical applications. Here, we have extensively developed and characterized blends of TPU/PCL and composites with 5, 10, and 20 wt% of hydroxyapatite (HA). The thermal, rheological, and mechanical characterizations showed that the blends present an intermediate behavior between pure TPU and PCL. The 75TPU/25PCL blend exhibited the best shape memory performance at temperatures below 50 °C. Filaments of this blend presented a fixation rate of 86.6% and a recovery rate of 73.3% at 50 ℃. The addition of HA had little influence on the shape memory properties; on the other hand, it strengthened the material, reaching elastic modulus values close to 100 MPa. In vitro tests revealed a biocompatible behavior for all blends, and the composite with 10 wt% HA from the 75TPU/25PCL blend demonstrated greater cell proliferation compared to the other composites. Graphical abstract: [Figure not available: see fulltext.]

Assuntos Scopus

Biomedical applications , Mechanical characterizations , Memory performance , Property , Rheological characterization , Shape memory polymers , Shape memory thermoplastic polyurethanes , Shape-memory , Thermal characterization , Thermoplastic polyurethanes