Pulmonary changes on high-resolution computed tomography of patients with rheumatoid arthritis and their association with clinical, demographic, serological and therapeutic variables

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dc.contributor.authorSkare T.L.
dc.contributor.authorNakano I.
dc.contributor.authorEscuissiato D.L.
dc.contributor.authorBatistetti R.
dc.contributor.authorde Oliveira Rodrigues T.
dc.contributor.authorSilva M.B.
dc.date.accessioned2024-03-13T01:10:56Z
dc.date.available2024-03-13T01:10:56Z
dc.date.issued2011
dc.description.abstractBackground: Extra-articular manifestations are found in up to 50% of the patients with rheumatoid arthritis (RA). Objective: To assess the prevalence of pulmonary changes on high-resolution computed tomography (HRCT) in patients with RA and their association with demographic, clinical, serological and therapeutic variables. Method: Seventy-one patients with RA were assessed regarding their age at RA onset, duration of disease, gender, tobacco use, presence of rheumatoid nodules, secondary Sjögren's syndrome, rheumatoid factor, presence of anti-CCP and antinuclear factor, respiratory complaints, use of medications, and pulmonary changes on HRCT. Results: HRCT changes were identified in 55% of the patients, the most common being the presence of ground glass opacities, parenchymal bands, traction bronchiectasis, and honeycombing. None of the clinical variables studied associated with the HRCT findings, except for duration of the disease, which was longer in patients with pulmonary nodules and reticular lesions (ground-glass opacity). Conclusions: There is a high prevalence of HRCT changes in patients with RA, which do not associate with clinical, serological, therapeutic and demographic variables, except for duration of disease. © Elsevier Editora Ltda.
dc.description.firstpage325
dc.description.issuenumber4
dc.description.lastpage337
dc.description.volume51
dc.identifier.issn0482-5004
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36969
dc.relation.ispartofRevista Brasileira de Reumatologia
dc.rightsAcesso Restrito
dc.subject.otherlanguagePulmonary lesion
dc.subject.otherlanguageRheumatoid arthritis
dc.subject.otherlanguageTomography
dc.titlePulmonary changes on high-resolution computed tomography of patients with rheumatoid arthritis and their association with clinical, demographic, serological and therapeutic variables
dc.typeArtigo
local.scopus.citations22
local.scopus.eid2-s2.0-79960588767
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79960588767&origin=inward
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