May the best friend be an enemy if not recognized early: Possible role of omega-3 against cardiovascular abnormalities due antipsychotics in the treatment of autism

Página do item simplificado
dc.contributor.authorCysneiros R.M.
dc.contributor.authorTerra V.C.
dc.contributor.authorMachado H.R.
dc.contributor.authorArida R.M.
dc.contributor.authorSchwartzman J.S.
dc.contributor.authorCavalheiro E.A.
dc.contributor.authorScorza F.A.
dc.date.accessioned2024-03-13T01:35:56Z
dc.date.available2024-03-13T01:35:56Z
dc.date.issued2009
dc.description.abstractAutism spectrum disorders (ASD) are neurodevelopment disorders that cause severe and pervasive impairment in socialization, communication, and behavior. Although the availability of antipsychotic treatment in ASD has expanded, we will be very careful with side effects of these pharmacological agents. Following this reasoning, emerging data indicate that some antipsychotics may be associated with cardiovascular adverse events (e.g., QT interval prolongation), suggesting that this could be correlated to sudden death. Quite interesting, substantial evidence from epidemiological and case-control studies indicates that omega-3 reduces the risk of cardiovascular mortality, particularly sudden cardiac death. In accordance to the above mentioned findings, as omega-3 fatty acids per se have a direct cardiovascular protective role, our paper hypothesized that omega-3 fatty acids supplementation in ASD patients treated with atypical antipsychotic drugs may reduce cardiac arrhythmias and hence sudden cardiac death.
dc.description.firstpage922
dc.description.issuenumber3 B
dc.description.lastpage926
dc.description.volume67
dc.identifier.doi10.1590/S0004-282X2009000500031
dc.identifier.issn1678-4227
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37431
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.rightsAcesso Aberto
dc.subject.otherlanguageAutism spectrum disorders
dc.subject.otherlanguageHeart
dc.subject.otherlanguageOmega-3
dc.subject.otherlanguageSudden death
dc.titleMay the best friend be an enemy if not recognized early: Possible role of omega-3 against cardiovascular abnormalities due antipsychotics in the treatment of autism
dc.typeArtigo de revisão
local.scopus.citations5
local.scopus.eid2-s2.0-71949094416
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=71949094416&origin=inward
Arquivos
Coleções
Artigos de periódico