Interference of Seasonal Variation on the Antimicrobial and Cytotoxic Activities of the Essential Oils from the Leaves of Iryanthera polyneura in the Amazon Rain Forest

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dc.contributor.authorMartins E.R.
dc.contributor.authorDiaz I.E.C.
dc.contributor.authorPaciencia M.L.B.
dc.contributor.authorFana S.A.
dc.contributor.authorMorais D.
dc.contributor.authorEberlin M.N.
dc.contributor.authorSilva J.S.
dc.contributor.authorSilveira E.R.
dc.contributor.authorBarros M.P.
dc.contributor.authorSuffredini I.B.
dc.date.accessioned2024-03-12T23:51:44Z
dc.date.available2024-03-12T23:51:44Z
dc.date.issued2019
dc.description.abstract© 2019 Wiley-VHCA AG, Zurich, SwitzerlandThe essential oils (EOs) obtained from the leaves of Iryanthera polyneura Ducke trees was chemically Assessed and tested for the ability of inhibiting the growth of Candida albicans, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans and S. sanguinis. The oil was also tested against breast (MCF-7) and prostate (PC-3) cancer cell lines. Minimum bactericidal concentrations (MBCs) and 50 % inhibition concentrations (IC50) values were obtained. EOs were active against Gram-positive bacteria. Spathulenol, α-cadinol and τ-muurolol were major components of EOs. The oils showed a higher cytotoxicity against PC-3 than MCF-7 cells, although the oils were active against both cell types. Oils obtained from leaves collected in the dry season were more active against E. faecalis, S. aureus and PC-3, while the oils obtained from leaves collected in the rainy season were more active against S. mutans, S. sanguinis and MCF-7. The antibacterial and cytotoxic activities of the essential oils from the leaves of I. polyneura are related to the seasonal climate variation and are influenced by compounds that are minor components of the oils.
dc.description.issuenumber10
dc.description.volume16
dc.identifier.doi10.1002/cbdv.201900374
dc.identifier.issn1612-1880
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35191
dc.relation.ispartofChemistry and Biodiversity
dc.rightsAcesso Restrito
dc.subject.otherlanguageAmazon rain forest
dc.subject.otherlanguageantibacterial activity
dc.subject.otherlanguagecanonical correspondence analysis
dc.subject.otherlanguageMyristicaceae
dc.subject.otherlanguageseasonality
dc.titleInterference of Seasonal Variation on the Antimicrobial and Cytotoxic Activities of the Essential Oils from the Leaves of Iryanthera polyneura in the Amazon Rain Forest
dc.typeArtigo
local.scopus.citations7
local.scopus.eid2-s2.0-85073528473
local.scopus.subjectAnti-Bacterial Agents
local.scopus.subjectAntineoplastic Agents, Phytogenic
local.scopus.subjectBrazil
local.scopus.subjectCell Proliferation
local.scopus.subjectDrug Screening Assays, Antitumor
local.scopus.subjectHumans
local.scopus.subjectMCF-7 Cells
local.scopus.subjectMicrobial Sensitivity Tests
local.scopus.subjectMyristicaceae
local.scopus.subjectOils, Volatile
local.scopus.subjectPC-3 Cells
local.scopus.subjectPlant Leaves
local.scopus.subjectRainforest
local.scopus.subjectSeasons
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85073528473&origin=inward
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