Flavonoids and fatty acids of Camellia japonica leaves extract
Tipo
Artigo
Data de publicação
2011
Periódico
Revista Brasileira de Farmacognosia
Citações (Scopus)
12
Autores
Azuma C.M.
dos Santos F.C.S.
Lago J.H.G.
dos Santos F.C.S.
Lago J.H.G.
Orientador
Título da Revista
ISSN da Revista
Título de Volume
Membros da banca
Programa
Resumo
The ethanol extract from the leaves of Camellia japonica L., Theaceae, showed antiradical potential in the DPPH test using TLC plates (SiO2). Aiming the isolation of active compounds, this extract was partitioned between BuOH:H2O (1:1) and the two obtained phases were also evaluated to detection of antiradical activity. The active BuOH phase was fractionated in Sephadex LH-20 and silica (normal or reverse phase) to afford three aglycone flavonoids (quercetin, kaempferol and apigenin), which have been described in the C. japonica at first time, two glycosilated flavonoids (rutin and quercetrin), and a mixture of saturated fatty acids. The structures of isolated compounds were defined by NMR and GC/MS analyses.