Cryptococcal osteomyelitis in a patient with multiple myeloma Osteomielite criptocócica em paciente com mieloma múltiplo
Tipo
Artigo
Data de publicação
2010
Periódico
Revista Brasileira de Hematologia e Hemoterapia
Citações (Scopus)
0
Autores
Nocera V.B.
Ronchi Jr. I.
Pietrovicz J.
Krebs C.N.V.
Lopes G.L.
Ronchi Jr. I.
Pietrovicz J.
Krebs C.N.V.
Lopes G.L.
Orientador
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ISSN da Revista
Título de Volume
Membros da banca
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Resumo
Cryptococcosis is a systemic fungal infection that can involve several organs, including the central nervous system, lungs and bones. The most common clinical presentation of this microorganism is meningitis however bone involvement has been reported in 5 to 10% of cases of systemic infections. Bone infections caused by Cryptococcus neoformans without other associated infections are extremely rare. The incidence is more common in immunocompromised patients, for example individuals on immunotherapy using corticosteroids or other immunosuppressants and those with sarcoidosis, tuberculosis and other malignancies. Here we report the case of a patient with multiple myeloma who presented with osteomyelitis due to C. neoformans: no other similar cases were found in the literature. The purpose of this report is to discuss the association of cryptococcosis in immunocompromised patients.