Liberação de princípios ativos revestidos com biosistemas poliméricos
dc.contributor.advisor | Miranda, Leila Figueiredo de | |
dc.contributor.advisor1Lattes | http://lattes.cnpq.br/0218222413589119 | por |
dc.contributor.author | Monção, Camila Paraiso | |
dc.creator.Lattes | http://lattes.cnpq.br/5389069932075516 | por |
dc.date.accessioned | 2018-11-14T13:27:04Z | |
dc.date.accessioned | 2020-12-07T15:07:14Z | |
dc.date.available | 2020-12-07T15:07:14Z | |
dc.date.issued | 2018-08-10 | |
dc.description.abstract | In this work the main characteristics, applications, potentialities and limitations of the controlled release systems were studied, as well as the mechanisms that directly influenced the release kinetics of the active agent. Micro and nanostructured systems have great potential for the controlled release and encapsulation of bioactive molecules. The various biodegradable polymer systems represent a new strategy for the delivery of active ingredients. A controlled release system enables the drug concentration profile to remain constant within the therapeutic range thereby promoting increased therapeutic index and immune response to the patient and avoiding adverse side effects when compared to conventional methods of administration. In this work were obtained membranes formed by polymeric biosystems for application in controlled release of drugs and other assets. Four release systems were obtained: beeswax / protein / lecithin; beeswax / protein / alginate / lecithin and beeswax / alginate / chitosan / lecithin by methods of complex coacervation and spray drying. The results show that the most effective system was bee / protein / alginate / lecithin. | eng |
dc.format | application/pdf | * |
dc.identifier.citation | MONÇÃO, Camila Paraiso. Liberação de princípios ativos revestidos com biosistemas poliméricos. 2018. 68 f. Dissertação( Engenharia de Materiais) - Universidade Presbiteriana Mackenzie, São Paulo. | por |
dc.identifier.uri | http://dspace.mackenzie.br/handle/10899/26505 | |
dc.keywords | controlled release | eng |
dc.keywords | encapsulation of bioactive molecules | eng |
dc.keywords | complex coacervation | eng |
dc.keywords | spray drying | eng |
dc.language | por | por |
dc.publisher | Universidade Presbiteriana Mackenzie | por |
dc.rights | Acesso Aberto | por |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | liberação controlada | por |
dc.subject | encapsulação de moléculas bioativas | por |
dc.subject | coacervação complexa | por |
dc.subject | spray drying | por |
dc.subject.cnpq | CNPQ::CIENCIAS DA SAUDE::FARMACIA | por |
dc.thumbnail.url | http://tede.mackenzie.br/jspui/retrieve/17641/Camila%20Para%c3%adso%20Mon%c3%a7%c3%a3o.pdf.jpg | * |
dc.title | Liberação de princípios ativos revestidos com biosistemas poliméricos | por |
dc.type | Dissertação | por |
local.contributor.board1 | Munhoz Junior, Antônio Hortêncio | |
local.contributor.board1Lattes | http://lattes.cnpq.br/8233884614933594 | por |
local.contributor.board2 | Silva, Leonardo Gondim de Andrade e | |
local.contributor.board2Lattes | http://lattes.cnpq.br/7388174990363675 | por |
local.publisher.country | Brasil | por |
local.publisher.department | Escola de Engenharia Mackenzie (EE) | por |
local.publisher.initials | UPM | por |
local.publisher.program | Engenharia de Materiais | por |
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