Transcranial direct current stimulation of the prefrontal cortex modulates the desire for specific foods

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dc.contributor.authorFregni F.
dc.contributor.authorOrsati F.
dc.contributor.authorPedrosa W.
dc.contributor.authorFecteau S.
dc.contributor.authorTome F.A.M.
dc.contributor.authorNitsche M.A.
dc.contributor.authorMecca T.
dc.contributor.authorMacedo E.C.
dc.contributor.authorPascual-Leone A.
dc.contributor.authorBoggio P.S.
dc.date.accessioned2024-03-13T01:37:28Z
dc.date.available2024-03-13T01:37:28Z
dc.date.issued2008
dc.description.abstractWe aimed to assess whether modulation of the dorsolateral prefrontal cortex (DLFPC) with noninvasive brain stimulation, namely transcranial direct current stimulation (tDCS), modifies food craving in healthy subjects. We performed a randomized sham-controlled cross-over study in which 23 subjects received sham and active tDCS (anode left/cathode right and anode right/cathode left) of the DLPFC. Subjects were exposed to food and also watched a movie of food associated with strong craving. Desire for food consumption was evaluated by visual analogue scales (VAS) and food consumption before and after treatment. In addition we measured visual attention to food using an eye tracking system. Craving for viewed foods as indexed by VAS was reduced by anode right/cathode left tDCS. After sham stimulation, exposure to real food or food-related movie increased craving; whereas after anode left/cathode right tDCS, the food-related stimuli did not increase craving levels, as revealed by the VAS scale. Moreover, compared with sham stimulation, subjects fixated food-related pictures less frequently after anode right/cathode left tDCS and consumed less food after both active stimulation conditions. These changes were not related to mood changes after any type of tDCS treatment. The effects of tDCS on food craving might be related to a modulation of neural circuits associated with reward and decision-making. © 2007 Elsevier Ltd. All rights reserved.
dc.description.firstpage34
dc.description.issuenumber1
dc.description.lastpage41
dc.description.volume51
dc.identifier.doi10.1016/j.appet.2007.09.016
dc.identifier.issn0195-6663
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37516
dc.relation.ispartofAppetite
dc.rightsAcesso Restrito
dc.subject.otherlanguageBrain polarization
dc.subject.otherlanguageBrain stimulation
dc.subject.otherlanguageFood craving
dc.subject.otherlanguageSmoking
dc.subject.otherlanguageSubstance addiction
dc.subject.otherlanguageTranscranial direct current stimulation
dc.titleTranscranial direct current stimulation of the prefrontal cortex modulates the desire for specific foods
dc.typeArtigo
local.scopus.citations232
local.scopus.eid2-s2.0-42749091607
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=42749091607&origin=inward
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