Yellow fever virus investigation in tissues of vampire bats Desmodus rotundus during a wild yellow fever outbreak in Brazilian Atlantic Forest

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dc.contributor.authorCupertino M.D.C.
dc.contributor.authorBayao T.D.S.
dc.contributor.authorXisto M.F.
dc.contributor.authorPaula S.O.
dc.contributor.authorRibeiro S.P.
dc.contributor.authorMontenegro S.S.P.
dc.contributor.authorFreitas M.B.
dc.contributor.authorGomes A.P.
dc.contributor.authorSiqueira-Batista R.
dc.date.accessioned2024-09-01T06:35:36Z
dc.date.available2024-09-01T06:35:36Z
dc.date.issued2022
dc.description.abstract© 2022 Elsevier LtdIn the last decade a large outbreak of Yellow Fever (YF) has been observed in Brazilian Atlantic Forest region, traditionally a non-endemic area. In this scenario, the role of wild mammal species as YF reservoirs can be questioned, especially the hematophagous bat, Desmodus rotundus. So, the objective of this study was to analyze molecularly the presence of the YF virus (YFV) in hematophagous bats during a YF outbreak in Brazil. Twenty-one samples were collected from seven adult male hematophagous bats D. rotundus. As YFV is considered a viscerotropic and neurotropic virus, samples of liver, kidney and brain were collected and molecularly analyzed using the RT qPCR technique. The animals were captured according to ethical protocols during a YF outbreak in Brazil in 2017, from a region of the Brazilian Atlantic Forest. The results revealed that the analyzed tissue samples were not infected with the YFV. The negative results for this bat species allow us to infer that other animals may be reservoirs of this virus in this ecosystem and they probably have not been identified yet. Therefore, health surveillance actions are essential to monitor the role of wild animals in the YF dissemination in Brazilian Atlantic Forest and alert to the possibility of new geographic amplification of areas where YF occurs. This research encourages the new search about the role of wild animals on YFV transmission and reinforces the importance of epidemiological surveillance in the transmission of human infectious diseases.
dc.description.volume89
dc.identifier.doi10.1016/j.cimid.2022.101869
dc.identifier.issnNone
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/39309
dc.relation.ispartofComparative Immunology, Microbiology and Infectious Diseases
dc.rightsAcesso Restrito
dc.subject.otherlanguageArboviruses
dc.subject.otherlanguageChiroptera
dc.subject.otherlanguageFlavivirus
dc.subject.otherlanguagePublic health
dc.subject.otherlanguageZoonoses
dc.titleYellow fever virus investigation in tissues of vampire bats Desmodus rotundus during a wild yellow fever outbreak in Brazilian Atlantic Forest
dc.typeArtigo
local.scopus.citations0
local.scopus.eid2-s2.0-85138051866
local.scopus.subjectAnimals
local.scopus.subjectBrazil
local.scopus.subjectChiroptera
local.scopus.subjectDisease Outbreaks
local.scopus.subjectEcosystem
local.scopus.subjectForests
local.scopus.subjectHumans
local.scopus.subjectMale
local.scopus.subjectYellow Fever
local.scopus.subjectYellow fever virus
local.scopus.updated2024-12-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85138051866&origin=inward
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