Arylboronic Acids and their Myriad of Applications Beyond Organic Synthesis

Página do item simplificado
dc.contributor.authorHiller N.D.J.
dc.contributor.authordo Amaral e Silva N.A.
dc.contributor.authorTavares T.A.
dc.contributor.authorFaria R.X.
dc.contributor.authorEberlin M.N.
dc.contributor.authorde Luna Martins D.
dc.date.accessioned2024-03-12T23:47:03Z
dc.date.available2024-03-12T23:47:03Z
dc.date.issued2020
dc.description.abstract© 2020 Wiley-VCH Verlag GmbH & Co. KGaA, WeinheimBoron organometallic compounds are mainly known for their great value in organic synthesis to construct biaryls in Suzuki couplings, for arylations of olefins, for C–S, C–O, and C–N couplings or as organometallic catalysts. Herein, using arylboronic acids (Ar-B(OH)2) as a illustrative case, we review the applications of these highly versatile molecules which expands much beyond their commonly perceived uses. Seeing primarily as “mere” intermediates in organic synthesis and organometallic catalysis, this review shows many examples of their uses in other areas of chemistry and seeks therefore to contribute to awaken scientists to the wide range of new possibilities that have been opened to boronorganic compounds, which have acted indeed as very versatile and attractive chemicals with much desirable characteristics such as safety, stability, and chemical diversity. Because the chemistry of boronic acids is extremely wide, we focused on arylboronic acids, which represent an illustrative case since their properties can be modulated by the nature of the ring or the ring substituents. Illustrative applications in analytical chemistry such as in chromatography and electrophoresis, as well as in probes to detect and quantify a variety of different chemical species and as derivatizing agents to determine enantiomeric excess in nuclear magnetic resonance spectroscopy are also given. Applications of arylboronic acids in areas as diverse as the chemistry of new materials to develop supramolecular architectures and in medical chemistry, including diagnostics, neutron capture therapy and as pharmaceutical drugs are also reviewed.
dc.description.firstpage4841
dc.description.issuenumber31
dc.description.lastpage4877
dc.description.volume2020
dc.identifier.doi10.1002/ejoc.202000396
dc.identifier.issn1099-0690
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/34929
dc.relation.ispartofEuropean Journal of Organic Chemistry
dc.rightsAcesso Restrito
dc.subject.otherlanguageArylboronic acids
dc.subject.otherlanguageBoron organometallics
dc.subject.otherlanguageCarbohydrates
dc.subject.otherlanguageDiols
dc.subject.otherlanguageSensors
dc.titleArylboronic Acids and their Myriad of Applications Beyond Organic Synthesis
dc.typeArtigo de revisão
local.scopus.citations34
local.scopus.eid2-s2.0-85085551608
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85085551608&origin=inward
Arquivos
Coleções
Artigos de periódico