Cognition and impulsivity in adults with attention deficit hyperactivity disorder with and without cocaine and/or crack dependence

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dc.contributor.authorMiguel C.S.
dc.contributor.authorMartins P.A.
dc.contributor.authorMoleda N.
dc.contributor.authorKlein M.
dc.contributor.authorChaim-Avancini T.
dc.contributor.authorGobbo M.A.
dc.contributor.authorAlves T.M.
dc.contributor.authorSilva M.A.
dc.contributor.authorLouza M.R.
dc.date.accessioned2024-03-13T00:53:48Z
dc.date.available2024-03-13T00:53:48Z
dc.date.issued2016
dc.description.abstract© 2016 Elsevier Ireland Ltd.Background: Substance use disorder (SUD) is a common comorbidity in adults with attention deficit-hyperactivity disorder (ADHD). However,there have been few studies on cognitive profiles of these patients. Impulsivity is also commonly increased in both disorders. The central aim of this study was to compare cognition and impulsivity in subjects who had ADHD and cocaine dependence (ADHD + COC group) to those with ADHD only (ADHD-noSUD group). We hypothesized that the ADHD + COC group would show more marked cognitive dysfunction and greater impulsivity than their counterparts with ADHD only. Methods: A total of 70 adult patients diagnosed with ADHD according to (DSM-IV-TR) criteria were enrolled; 36 with ADHD + COC and 34 with ADHD-noSUD. All study participants were evaluated with a sociodemographic questionnaire; the Mini International Neuropsychiatric Interview; the Adult ADHD Self-Report Scale; the Addiction Severity Index; the Alcohol, Smoking and Substance Involvement Screening Test; the Barratt Impulsiveness Scale; and a comprehensive neurocognitive battery. Results: Compared to individuals with ADHD-noSUD, ADHD + COC individuals had significantly lower mean IQ and higher motor impulsivity. On average, the ADHD + COC group also performed more poorly on tasks assessing verbal skills, vigilance, implicit learning during decision making, and ADHD-noSUD performed more poorly on selective attention, information processing, and visual search. Conclusions: Our results support the integrative theory of ADHD based on the cognitive and affective neuroscience model, and suggests that ADHD-noSUD patients have impairments in cognitive regulation, while ADHD + COC patients have impairments in both cognitive and affective regulation.
dc.description.firstpage97
dc.description.lastpage104
dc.description.volume160
dc.identifier.doi10.1016/j.drugalcdep.2015.12.040
dc.identifier.issn1879-0046
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36005
dc.relation.ispartofDrug and Alcohol Dependence
dc.rightsAcesso Restrito
dc.subject.otherlanguageAttention deficit disorder with hyperactivity
dc.subject.otherlanguageCocaine
dc.subject.otherlanguageCognition
dc.subject.otherlanguageDecision making
dc.subject.otherlanguageImpulsivity
dc.titleCognition and impulsivity in adults with attention deficit hyperactivity disorder with and without cocaine and/or crack dependence
dc.typeArtigo
local.scopus.citations24
local.scopus.eid2-s2.0-84960128850
local.scopus.subjectAdult
local.scopus.subjectAttention
local.scopus.subjectAttention Deficit Disorder with Hyperactivity
local.scopus.subjectCocaine-Related Disorders
local.scopus.subjectCognition
local.scopus.subjectCognition Disorders
local.scopus.subjectDiagnosis, Dual (Psychiatry)
local.scopus.subjectDiagnostic and Statistical Manual of Mental Disorders
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectImpulsive Behavior
local.scopus.subjectMale
local.scopus.subjectSurveys and Questionnaires
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84960128850&origin=inward
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