Rheumatic manifestations in brazilian patients with AIDS

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dc.contributor.authorTelles J.P.
dc.contributor.authorGrande M.A.
dc.contributor.authorJurgensen A.
dc.contributor.authorHecke J.C.
dc.contributor.authorSkare T.
dc.contributor.authorNisihara R.M.
dc.contributor.authorCamargo R.
dc.date.accessioned2024-03-13T01:01:41Z
dc.date.available2024-03-13T01:01:41Z
dc.date.issued2014
dc.description.abstractIntroduction: Patients with AIDS (acquired immunodeficiency syndrome) may have rheumatic complaints such as arthritis and arthralgia, dry eyes, increased salivary glands, lower back pain, enthesitis etc. Autoantibodies like ANA (antinuclear antibody) and RF (rheumatoid factor) may also be present. Objective: To study the prevalence of rheumatic complaints in AIDS patients and correlate them with the presence of ANA and RF. Methods: We studied 69 patients with AIDS (28.9% women and 71.0% men) with a mean age of 40.8 ± 8.9 years, median disease duration of 60 months, for rheumatic complaints, ANA, ENA-6 (anti-Ro, anti-La, anti--Sm, anti-RNP, anti-Scl70 and anti-Jo1) and RF. We collected demographic data, CD4+ and CD8+ cell count and values of viral load. Results: Arthralgia was present in 39.1%, sicca symptoms in 21.7%, inflammatory lumbar pain in 13.4%, enthesopathy in 6.6%, parotid enlargement in 1.4%, RF in 10.1% and ANA in 8.6%. All patients were negative for ENA-6. ANA was more common in older patients (p = 0.03) and in those with higher viral load (p = 0.006). No association was found with the presence of RF. Conclusions: The most common manifestation in this context was arthralgia. ANA presence was associated with age of the patients and viral load.
dc.description.firstpage143
dc.description.issuenumber2
dc.description.lastpage145
dc.description.volume39
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/36449
dc.relation.ispartofActa Reumatologica Portuguesa
dc.rightsAcesso Restrito
dc.subject.otherlanguageAcquired immunodeficiency syndrome
dc.subject.otherlanguageArthritis
dc.subject.otherlanguageAutoantibodies
dc.subject.otherlanguageRheumatoid factor
dc.titleRheumatic manifestations in brazilian patients with AIDS
dc.typeArtigo
local.scopus.citations4
local.scopus.eid2-s2.0-84908368924
local.scopus.subjectAcquired Immunodeficiency Syndrome
local.scopus.subjectAdult
local.scopus.subjectBrazil
local.scopus.subjectFemale
local.scopus.subjectHumans
local.scopus.subjectMale
local.scopus.subjectPrevalence
local.scopus.subjectRheumatic Diseases
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84908368924&origin=inward
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