Dataset on sociability, cognitive function, gene and protein expression of molecules involved in social behavior, reward system and synapse function following early-life status epilepticus in Wistar rats

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dc.contributor.authorPacifico A.M.
dc.contributor.authorBatista S.P.
dc.contributor.authorRibeiro F.T.
dc.contributor.authorSantos P.B.D.
dc.contributor.authorSilveira G.B.
dc.contributor.authorPedrico do Nascimento B.P.
dc.contributor.authorJunior E.D.
dc.contributor.authorBarbosa G.H.L.
dc.contributor.authorRibeiro M.O.
dc.contributor.authorda Silva S.G.
dc.contributor.authorCysneiros R.M.
dc.date.accessioned2024-03-12T23:47:16Z
dc.date.available2024-03-12T23:47:16Z
dc.date.issued2020
dc.description.abstract© 2020 The Author(s)Early-life status epilepticus produces deficit in social interaction and vocalization, enhances anxiety, no cognitive impairment and alters functional connectivity within the hippocampus (CA3-CA1) and between the hippocampus and prefrontal cortex [1–12], but the underlying mechanisms remain unknown. This data article contains behavioral and molecular data of the adult male Wistar rats subjected to early life pilocarpine-induced seizures. Animal's behaviors were assessed to social memory and social motivation, working and reference memories and cognitive flexibility. The brain tissues (hypothalamus, hippocampus, amygdala, and striatum) were probed to gene and protein expression of molecules related to social behavior, reward system and synaptic function.
dc.description.volume31
dc.identifier.doi10.1016/j.dib.2020.105819
dc.identifier.issn2352-3409
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/34941
dc.relation.ispartofData in Brief
dc.rightsAcesso Aberto
dc.subject.otherlanguageCognition
dc.subject.otherlanguageEarly-life status epilepticus
dc.subject.otherlanguageMotivation
dc.subject.otherlanguageOxytocin
dc.subject.otherlanguagePilocarpine
dc.subject.otherlanguageSociability
dc.titleDataset on sociability, cognitive function, gene and protein expression of molecules involved in social behavior, reward system and synapse function following early-life status epilepticus in Wistar rats
dc.typeArtigo
local.scopus.citations3
local.scopus.eid2-s2.0-85086598404
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086598404&origin=inward
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