Infectious keratitis in Southern Brazil: A comparison culture negative and culture positive patients Ceratite infecciosa no sul do Brasil: Comparação entre pacientes com cultura negativa e positiva

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dc.contributor.authorDuarte M.C.B.
dc.contributor.authorBecker G.N.
dc.contributor.authorMuller G.G.
dc.contributor.authorTuon F.F.
dc.date.accessioned2024-03-12T23:50:20Z
dc.date.available2024-03-12T23:50:20Z
dc.date.issued2020
dc.description.abstract© 2019 Sociedade Brasileira de Oftalmologia.Purpose: To compare clinical-epidemiological profile and treatment outcome between culture negative and culture positive keratitis patients. Methods: Patients with suspected infectious keratitis seen at two ophthalmic hospitals in Curitiba, Brazil, between June 2014 and April 2016, were prospectively studied. Ophthalmological exam with corneal scraping and microbiological tests were performed. Data regarding follow up, surgical interventions and treatment outcome were collected after 12 weeks of the first visit trough medical chart review. From the results of the culture, two groups were formed: culture negative keratitis (CNK) and culture positive keratitis (CPK). Results: According to inclusion criteria 21 patients were classified as culture negative keratitis and 20 patients as culture positive keratitis. The number of patients on antibiotic drops at the first visit was greater in CNK group (90.5% versus 60%; p=0.032). Surgical procedures were necessary in 3 patients (15%) in CNK group and in 7 patients (36,8%) in CPK group (p=0.155). Treatment success was achieved by 85% (17/20) of the patients in CNK group and by 61% (11/18) of the patients in CPK group (p=0.144). There was no significant difference between groups regarding age, gender, place of residence, presence of comorbidities, risk factors for infectious keratitis, duration of symptoms and characteristics of corneal ulcer. Conclusions: Previous treatment with antibiotics correlates with negative culture results. There was no significant difference in treatment outcome between culture negative and culture positive keratitis patients.
dc.description.firstpage46
dc.description.issuenumber1
dc.description.lastpage52
dc.description.volume79
dc.identifier.doi10.5935/0034-7280.20200009
dc.identifier.issn1982-8551
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35114
dc.relation.ispartofRevista Brasileira de Oftalmologia
dc.rightsAcesso Restrito
dc.subject.otherlanguageAntibiotic drops
dc.subject.otherlanguageCorneal ulcer
dc.subject.otherlanguageInfectious keratitis
dc.subject.otherlanguageMicrobial culture
dc.subject.otherlanguageMicrobial keratitis
dc.titleInfectious keratitis in Southern Brazil: A comparison culture negative and culture positive patients Ceratite infecciosa no sul do Brasil: Comparação entre pacientes com cultura negativa e positiva
dc.typeArtigo
local.scopus.citations3
local.scopus.eid2-s2.0-85081248976
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081248976&origin=inward
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