Clinical predictors associated with duration of repetitive transcranial magnetic stimulation treatment for remission in bipolar depression: A naturalistic study

Página do item simplificado
dc.contributor.authorCohen R.B.
dc.contributor.authorBrunoni A.R.
dc.contributor.authorBoggio P.S.
dc.contributor.authorFregni F.
dc.date.accessioned2024-03-13T01:31:00Z
dc.date.available2024-03-13T01:31:00Z
dc.date.issued2010
dc.description.abstractRepetitive transcranial magnetic stimulation (rTMS) has been widely tested and shown to be effective for unipolar depression. Although it has also been investigated for bipolar depression (BD), there are only few rTMS studies with BD. Here, we investigated 56 patients with BD who received rTMS treatment until remission (defined as Hamilton Depression Rating Scores ≤7). We used simple and multiple logistic regressions to identify clinical and demographic predictors associated with duration of treatment (defined as <15 vs. >15 rTMS sessions). Age, refractoriness, number of prior depressive episodes, and severe depression at baseline were associated with a longer rTMS treatment. In the multivariate analysis, refractoriness (likelihood ratio (LR) = 4.33; p < 0.01) and baseline severity (LR = 0.18, p < 0.01) remained significant predictors. Our preliminary study showed that, in remitted patients, refractoriness and severity of index episode are associated with the need of a longer rTMS treatment; providing preliminary evidence of important factors associated with rTMS parameters adjustment. Copyright © 2010 by Lippincott Williams & Wilkins.
dc.description.firstpage679
dc.description.issuenumber9
dc.description.lastpage681
dc.description.volume198
dc.identifier.doi10.1097/NMD.0b013e3181ef2175
dc.identifier.issn0022-3018
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37155
dc.relation.ispartofJournal of Nervous and Mental Disease
dc.rightsAcesso Restrito
dc.subject.otherlanguageBipolar disorder
dc.subject.otherlanguageclinical trial
dc.subject.otherlanguagemajor depressive disorder
dc.subject.otherlanguagepredictors of response
dc.subject.otherlanguagerepetitive transcranial magnetic stimulation
dc.titleClinical predictors associated with duration of repetitive transcranial magnetic stimulation treatment for remission in bipolar depression: A naturalistic study
dc.typeArtigo
local.scopus.citations33
local.scopus.eid2-s2.0-77957086223
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77957086223&origin=inward
Arquivos
Coleções
Artigos de periódico