Fecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis Níveis de calprotectina fecal na uveite anterior aguda em pacientes com espondiloartrites

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dc.contributor.authorGazim C.C.
dc.contributor.authorde Borba A.A.
dc.contributor.authorde Castro G.K.P.
dc.contributor.authorSimioni J.
dc.contributor.authorGehlen M.L.
dc.contributor.authorRamos O.
dc.contributor.authorSkare T.L.
dc.date.accessioned2024-09-01T06:34:59Z
dc.date.available2024-09-01T06:34:59Z
dc.date.issued2023
dc.description.abstract© 2023, Arquivos Brasileiros de Oftalmologia. All Rights Reserved.Purpose: This study measured fecal calprotectin levels in a series of patients with anterior uveitis in order to determine whether anterior uveitis patients with associated spondyloarthritis have higher levels of fecal calprotectin than patients with anterior uveitis of other etiologies. A third group of patients with spondyloarthritis without uveitis was also evaluated to understand the role of acute anterior uveitis in increasing fecal calprotectin. Methods: In this cross-sectional study, 28 patients were divided into three groups: (a) Group 1, spondyloarthritis and uveitis (n=9); (b) Group 2, spondyloarthritis without uveitis (n=10); and (c) Group 3, uveitis without spondyloarthritis (n=9). The levels of fecal calprotectin were determined. Results: Groups 1 and 2 showed higher median fecal calprotectin levels (101.0 and 93.0 μg/g, respectively) compared with Group 3 (9.0 μg/g) (p=0.02). However, no relationship between fecal calprotectin levels and the presence of uveitis with spondyloarthritis could be demonstrated. Conclusion: Patients with spondyloarthritis with or without acute anterior uveitis have significantly elevated levels of fecal calprotectin. This test may be useful for differentiating spondyloarthrit-associated uveitis from uveitis of other etiologies.
dc.description.firstpage33
dc.description.issuenumber1
dc.description.lastpage37
dc.description.volume86
dc.identifier.doi10.5935/0004-2749.20230008
dc.identifier.issnNone
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/39308
dc.relation.ispartofArquivos Brasileiros de Oftalmologia
dc.rightsAcesso Aberto
dc.subject.otherlanguageBiomarkers
dc.subject.otherlanguageCalprotectin
dc.subject.otherlanguageInflammatory bowel diseases
dc.subject.otherlanguageSpondyloarthritis
dc.subject.otherlanguageUveitis
dc.titleFecal calprotectin levels in acute anterior uveitis in patients with spondyloarthritis Níveis de calprotectina fecal na uveite anterior aguda em pacientes com espondiloartrites
dc.typeArtigo
local.scopus.citations0
local.scopus.eid2-s2.0-85143645027
local.scopus.subjectCross-Sectional Studies
local.scopus.subjectHumans
local.scopus.subjectLeukocyte L1 Antigen Complex
local.scopus.subjectUveitis, Anterior
local.scopus.updated2024-10-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85143645027&origin=inward
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