C-glycosyl flavones from Peperomia blanda

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Artigo
Data de publicação
2009
Periódico
Fitoterapia
Citações (Scopus)
46
Autores
Velozo L.S.M.
Ferreira M.J.P.
Santos M.I.S.
Moreira D.L.
Guimaraes E.F.
Emerenciano V.P.
Kaplan M.A.C.
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The methanol extract from aerial parts of the Peperomia blanda (Piperaceae) yielded two C-glycosyl-flavones. Their structures were elucidated on the basis of extensive spectroscopic analysis, including 1D and 2D NMR, chemical transformation and comparison with the related known compounds. The structure of the new flavonoids were established as 4′-methoxy-vitexin 7-O-β-d-xylopyranoside (1) (7-O-β-d-xylopyranosyl-8-C-β-d-glucopyranosyl-4′-methoxy -apigenin) and vicenin-2 (2). The antioxidant activity of both compounds was investigated using the DPPH assay. Both compounds showed only modest activity, with IC50 values of 357.2 μM for 1, and 90.5 μM for 2. © 2008 Elsevier B.V. All rights reserved.
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