Antimicrobial and anti-biofilm properties of polypropylene meshes coated with metal-containing DLC thin films

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dc.contributor.authorCazalini E.M.
dc.contributor.authorMiyakawa W.
dc.contributor.authorTeodoro G.R.
dc.contributor.authorSobrinho A.S.S.
dc.contributor.authorMatieli J.E.
dc.contributor.authorMassi M.
dc.contributor.authorKoga-Ito C.Y.
dc.date.accessioned2024-03-13T00:49:25Z
dc.date.available2024-03-13T00:49:25Z
dc.date.issued2017
dc.description.abstract© 2017, Springer Science+Business Media New York.Abstract: A promising strategy to reduce nosocomial infections related to prosthetic meshes is the prevention of microbial colonization. To this aim, prosthetic meshes coated with antimicrobial thin films are proposed. Commercial polypropylene meshes were coated with metal-containing diamond-like carbon (Me-DLC) thin films by the magnetron sputtering technique. Several dissimilar metals (silver, cobalt, indium, tungsten, tin, aluminum, chromium, zinc, manganese, tantalum, and titanium) were tested and compositional analyses of each Me-DLC were performed by Rutherford backscattering spectrometry. Antimicrobial activities of the films against five microbial species (Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis) were also investigated by a modified Kirby-Bauer test. Results showed that films containing silver and cobalt have inhibited the growth of all microbial species. Tungsten-DLC, tin-DLC, aluminum-DLC, zinc-DLC, manganese-DLC, and tantalum-DLC inhibited the growth of some strains, while chromium- and titanium-DLC weakly inhibited the growth of only one tested strain. In-DLC film showed no antimicrobial activity. The effects of tungsten-DLC and cobalt-DLC on Pseudomonas aeruginosa biofilm formation were also assessed. Tungsten-DLC was able to significantly reduce biofilm formation. Overall, the experimental results in the present study have shown new approaches to coating polymeric biomaterials aiming antimicrobial effect. Graphical Abstract: [InlineMediaObject not available: see fulltext.].
dc.description.issuenumber6
dc.description.volume28
dc.identifier.doi10.1007/s10856-017-5910-y
dc.identifier.issn1573-4838
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/35760
dc.relation.ispartofJournal of Materials Science: Materials in Medicine
dc.rightsAcesso Restrito
dc.titleAntimicrobial and anti-biofilm properties of polypropylene meshes coated with metal-containing DLC thin films
dc.typeArtigo
local.scopus.citations34
local.scopus.eid2-s2.0-85020019246
local.scopus.subjectAnti-microbial activity
local.scopus.subjectAnti-microbial effects
local.scopus.subjectCompositional analysis
local.scopus.subjectMetal-containing diamond-like carbon
local.scopus.subjectMicrobial colonization
local.scopus.subjectPolymeric biomaterials
local.scopus.subjectPseudomonas aeruginosa
local.scopus.subjectRutherford back-scattering spectrometry
local.scopus.subjectAnti-Bacterial Agents
local.scopus.subjectAnti-Infective Agents
local.scopus.subjectBacterial Adhesion
local.scopus.subjectBiofilms
local.scopus.subjectCandida albicans
local.scopus.subjectCarbon
local.scopus.subjectChromium
local.scopus.subjectCoated Materials, Biocompatible
local.scopus.subjectCobalt
local.scopus.subjectDiamond
local.scopus.subjectEnterococcus faecalis
local.scopus.subjectEscherichia coli
local.scopus.subjectHumans
local.scopus.subjectMetals
local.scopus.subjectMicrobial Sensitivity Tests
local.scopus.subjectPolypropylenes
local.scopus.subjectPseudomonas aeruginosa
local.scopus.subjectSilver
local.scopus.subjectStaphylococcus aureus
local.scopus.subjectSurface Properties
local.scopus.subjectTantalum
local.scopus.subjectTitanium
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85020019246&origin=inward
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