High sensitivity, low-cost, and disposability: A novel screen-printed electrode developed for direct electrochemical detection of the antibiotic ceftriaxone

dc.contributor.authorSilva F.W.L.
dc.contributor.authorName L.L.
dc.contributor.authorTiba D.Y.
dc.contributor.authorBraz B.F.
dc.contributor.authorSantelli R.E.
dc.contributor.authorCanevari T.C.
dc.contributor.authorCincotto F.H.
dc.date.accessioned2024-03-12T19:07:39Z
dc.date.available2024-03-12T19:07:39Z
dc.date.issued2024
dc.description.abstract© 2023This study describes the development of a novel disposable and low-cost electrochemical platform for detecting the antibiotic ceftriaxone. The screen-printed electrode has been modified with a novel hybrid nanostructure containing silicon oxide (SiO2), zirconium oxide (ZrO2), and nitrogen-doped carbon quantum dots (Cdot-N). Different techniques like Fourier-transform infrared spectroscopy, Raman spectroscopy, and transmission electron microscopy characterized the hybrid nanostructure used in the sensor surface modifier material. The hybrid nanostructure showed an excellent synergistic effect that contributed to the oxidation reaction of ceftriaxone. The screen-printed electrode modified with SiO2/ZrO2/Cdot-N nanostructure presented high sensitivity with a detection limit of 0.2 nmol L−1 in the linear range of 0.0078–40.02 μmol L−1. The measurements have been performed by square wave voltammetry technique. Studies on real samples of synthetic urine, urine, and tap water showed 95%–105% recovery without applying any sample pretreatment. The sensor demonstrated excellent selectivity in the antibiotic ceftriaxone determination in the presence of possible interferences cationic, Na+, K+, Ca2+, Mg2+, Cu2+, Pb2+, Mn2+, Zn2+, Co2+, and biological, glucose, caffeine, uric acid, and ascorbic acid. The developed sensor becomes a selective, sensitive, and applicable tool in determining the antibiotic ceftriaxone.
dc.description.volume266
dc.identifier.doi10.1016/j.talanta.2023.125075
dc.identifier.issn0039-9140
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/33976
dc.relation.ispartofTalanta
dc.rightsAcesso Restrito
dc.subject.otherlanguageCeftriaxone
dc.subject.otherlanguageDisposable
dc.subject.otherlanguageElectrochemical sensor
dc.subject.otherlanguageLow-cost
dc.subject.otherlanguageQuantum dots. hybrid nanostructure
dc.titleHigh sensitivity, low-cost, and disposability: A novel screen-printed electrode developed for direct electrochemical detection of the antibiotic ceftriaxone
dc.typeArtigo
local.scopus.citations0
local.scopus.eid2-s2.0-85167822796
local.scopus.subjectCeftriaxone
local.scopus.subjectDisposables
local.scopus.subjectELectrochemical detection
local.scopus.subjectElectrochemical platforms
local.scopus.subjectHigh sensitivity
local.scopus.subjectHybrid nanostructures
local.scopus.subjectLow-costs
local.scopus.subjectNitrogen-doped carbons
local.scopus.subjectQuantum dot.
local.scopus.subjectScreen printed electrodes
local.scopus.subjectAnti-Bacterial Agents
local.scopus.subjectCeftriaxone
local.scopus.subjectElectrodes
local.scopus.subjectQuantum Dots
local.scopus.subjectSilicon Dioxide
local.scopus.updated2024-06-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85167822796&origin=inward
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