Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth

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dc.contributor.authorYamaguchi L.F.
dc.contributor.authorLago J.H.G.
dc.contributor.authorTanizaki T.M.
dc.contributor.authorMascio P.D.
dc.contributor.authorKato M.J.
dc.date.accessioned2024-03-13T01:42:11Z
dc.date.available2024-03-13T01:42:11Z
dc.date.issued2006
dc.description.abstractGrowing evidence suggests that RNOS (reactive nitrogen and oxygen species) are involved in the damage of biomolecules, contributing to the aetiology of several human diseases. Thus, the demand for antioxidants has stimulated the search for new compounds with potential use in this field. The in vitro antioxidant potential of prenylated hydroquinones and prenylated 4-hydroxy-benzoic acids from fruits of P. crassinervium was evaluated in terms of their capacity to suppress both DPPH (2,2-diphenyl-1-picrylhydrazyl) radical and chemiluminescence produced from luminol, using 2,2′-azo-bis(2-amidinopropane) (ABAP) as a peroxyl radical source. The inhibition of lipid peroxidation was assessed using liposomes from phosphatidylcholine as a membrane model. The prenylated hydroquinones had higher antioxidant activity than the benzoic acids and, among the hydroquinones, the E isomer was more efficient than the Z isomer. © 2006 Elsevier Ltd. All rights reserved.
dc.description.firstpage1838
dc.description.issuenumber16
dc.description.lastpage1843
dc.description.volume67
dc.identifier.doi10.1016/j.phytochem.2006.03.001
dc.identifier.issn0031-9422
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/37772
dc.relation.ispartofPhytochemistry
dc.rightsAcesso Restrito
dc.subject.otherlanguageAntioxidants
dc.subject.otherlanguageChemiluminscence
dc.subject.otherlanguageDPPH
dc.subject.otherlanguageLipoperoxidation
dc.subject.otherlanguagePiper crassinervium
dc.subject.otherlanguagePiperaceae
dc.subject.otherlanguagePrenylated benzoic acids
dc.subject.otherlanguagePrenylated hydroquinones
dc.titleAntioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth
dc.typeArtigo
local.scopus.citations56
local.scopus.eid2-s2.0-33747329539
local.scopus.updated2024-05-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33747329539&origin=inward
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