Neuropsychological profile of patients with infectious disease: characterization and comparison of patients with HIV, HTLV, and HCV

Tipo
Artigo
Data de publicação
2023
Periódico
Journal of NeuroVirology
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0
Autores
Gascon M.R.P.
de Oliveira G.S.
Laurence P.G.
Gualqui C.F.
de Oliveira A.C.P.
Smid J.
Fonseca L.A.M.
Casseb J.
Macedo E.C.
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Resumo
© 2022, Journal of NeuroVirology, Inc.Understanding the effect of the HIV, HTLV-1, and HCV viruses on cognitive aspects can help in the better characterization of dementia, as well as the best conducts to be suitable for rehabilitation. Thus, the present study aimed to characterize and compare the neuropsychological profile of 3 groups of patients with infectious diseases: HIV, HTLV, and HCV. The results of neuropsychological assessments and depression assessment of 325 people treated at a referral hospital for infectious diseases were analyzed, being 120 HIV carriers (74 (61.7%) men) with an average age of 47.5 years (SD = 10.3), 65 patients with HTLV-1 (16 (24.6%) men) with a mean age of 49.9 years (SD = 12.9), and 87 HCV patients (47 (54%) men) with a mean age of 55.5 years (SD = 11.2). In addition, 54 people (26 (48.1%) men) with negative serology who made up the control group were evaluated. The results of the statistical evaluation of the sociodemographic factors of the four groups (HIV, HTLV-1, HCV, and control) showed that in addition to age, schooling was a significant factor among them and may have a strong influence on the performance of cognitive tests. The HTLV-1 group had the lowest neurocognitive performance and also the highest rate of depressive symptoms.
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Assuntos Scopus
Communicable Diseases , Female , Hepatitis C , HIV Infections , HTLV-I Infections , Human T-lymphotropic virus 1 , Humans , Male , Middle Aged
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