How and Why to Investigate Multicomponent Reactions Mechanisms? A Critical Review

dc.contributor.authorRodrigues M.O.
dc.contributor.authorEberlin M.N.
dc.contributor.authorNeto B.A.D.
dc.date.accessioned2024-03-12T19:19:08Z
dc.date.available2024-03-12T19:19:08Z
dc.date.issued2021
dc.description.abstract© 2021 The Chemical Society of Japan & Wiley-VCH GmbH.We review the most innovative efforts and greatest challenges faced when elucidating multicomponent reactions (MCRs) mechanisms. When compared to traditional reactions, the often two or more concurrent reactions pathways and the greater number of possible intermediates in MCRs turn their mechanistic investigation both a harder and trickier task. The common approaches used to investigate reaction mechanisms are often unable to clarify MCRs mechanisms; hence few but clever approaches are currently used to determine these mechanisms and to depict their key transformations. Their complexity has required most innovative approaches and the use of a number of unique techniques that have shed light over the favored pathway selected from the myriad of alternatives theoretically available for MCRs. This review focuses on the most successful efforts applied by a few leading groups to perform these puzzlingly investigations.
dc.description.firstpage2762
dc.description.issuenumber10
dc.description.lastpage2781
dc.description.volume21
dc.identifier.doi10.1002/tcr.202000165
dc.identifier.issn1528-0691
dc.identifier.urihttps://dspace.mackenzie.br/handle/10899/34586
dc.relation.ispartofChemical Record
dc.rightsAcesso Restrito
dc.subject.otherlanguageMass spectrometry
dc.subject.otherlanguageMCRs
dc.subject.otherlanguageMechanism
dc.subject.otherlanguageMulticomponent reaction
dc.subject.otherlanguageReview
dc.titleHow and Why to Investigate Multicomponent Reactions Mechanisms? A Critical Review
dc.typeArtigo de revisão
local.scopus.citations29
local.scopus.eid2-s2.0-85100505828
local.scopus.updated2024-06-01
local.scopus.urlhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85100505828&origin=inward
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